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BACKGROUND This open-label pilot study is aimed to evaluate the efficacy and tolerability of the antidepressant duloxetine, which is effective for diabetic neuropathic pain, in the treatment of chronic oxaliplatin-induced peripheral neuropathy (OIPN). METHODS We enrolled a total of 39 patients with stage III or IV colorectal cancer with chronic OIPN. They(More)
BACKGROUNDS Apolipoprotein E epsilon-4 (APOE ε4) allele, methylenetetrahydrofolate reductase (MTHFR C677T), and methionine synthase (MTR A2756G) were tested their associations with cognitive impairment in people with late-life depression (LLD). METHODS People with LLD were assessed by mini-mental state examination and were examined the distribution of(More)
OBJECTIVE Patients with late-onset depression (LOD) have been reported to run a higher risk of subsequent dementia. The present study was conducted to assess whether statins can reduce the risk of dementia in these patients. METHODS We used the data from National Health Insurance of Taiwan during 1996-2009. Standardized Incidence Ratios (SIRs) were(More)
Speciation and possible reaction paths of nanosize copper pollutants extracted with a RTIL (room-temperature ionic liquid ([C4mim][PF6], 1-butyl-3-methylimidazolium hexafluorophosphate)) have been studied in the present work. Experimentally, in a very short contact time (2 min), 80-95% of nanosize CuO as well as other forms of copper (such as nanosize Cu,(More)
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