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Tumor necrosis factor (TNFalpha) receptor signaling can simultaneously activate caspase 8, the transcription factor, NF-kappaB and the kinase, JNK. While activation of caspase 8 is required for TNFalpha-induced apoptosis, and induction of NF-kappaB inhibits cell death, the precise function of JNK activation in TNFalpha signaling is not clearly understood.(More)
JNK contributes to TNF␣-mediated apoptosis remains Molecular and Cellular Biology to be addressed. Baylor College of Medicine The intrinsic apoptotic pathway is the result of activa-Houston, Texas 70030 tion of mitochondria-mediated cell death events, including changes in mitochondrial membrane permeability and subsequent release of proapoptotic factors(More)
Path planning is a fundamental problem, especially for various AEC applications, such as architectural design, indoor and outdoor navigation, and emergency evacuation. However, the conventional approaches mainly operate path planning on 2D drawings or building layouts by simply considering geometric information, while losing abundant semantic information of(More)
  • Khalid Abdelkarim Omer Matar, Xiaofeng Chen, Dongjie Chen, Wilfred Mabeche Anjago, Justice Norvienyeku, Yahong Lin +4 others
  • 2016
Carbon catabolite repression (CCR) is a common regulatory mechanism used by microorganisms to prioritize use of a preferred carbon source (usually glucose). The CreC WD40-repeat protein is a major component of the CCR pathway in Aspergillus nidulans. To clarify the function of the CreC ortholog from Magnaporthe oryzae in regulating gene expression important(More)
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