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Anterior-Posterior Guidance of Commissural Axons by Wnt-Frizzled Signaling
Commissural neurons in the mammalian dorsal spinal cord send axons ventrally toward the floor plate, where they cross the midline and turn anteriorly toward the brain; a gradient ofExpand
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Squeezing Axons Out of the Gray Matter A Role for Slit and Semaphorin Proteins from Midline and Ventral Spinal Cord
Commissural axons cross the nervous system midline and then turn to grow alongside it, neither recrossing nor projecting back into ventral regions. In Drosophila, the midline repellent Slit preventsExpand
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Sources of Work‐Family Conflict: A Sino‐U.S. Comparison of the Effects of Work and Family Demands
Given differences in values about work and family time, we hypothesize that Americans will experience greater family demand, which will have greater impact on work‐family conflict, whereas theExpand
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Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract
Guidance cues along the longitudinal axis of the CNS are poorly understood. Wnt proteins attract ascending somatosensory axons to project from the spinal cord to the brain. Here we show that WntExpand
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Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance.
Although a growing body of evidence supports that Wnt-Frizzled signaling controls axon guidance from vertebrates to worms, whether and how this is mediated by planar cell polarity (PCP) signalingExpand
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Wnt–Ryk signalling mediates medial–lateral retinotectal topographic mapping
Computational modelling has suggested that at least two counteracting forces are required for establishing topographic maps. Ephrin-family proteins are required for both anterior–posterior andExpand
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Binding of DCC by Netrin-1 to Mediate Axon Guidance Independent of Adenosine A2B Receptor Activation
Netrins stimulate and orient axon growth through a mechanism requiring receptors of the DCC family. It has been unclear, however, whether DCC proteins are involved directly in signaling or are mereExpand
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Sleep-disordered breathing children
ObjectiveTo assess the clinical significance of nasal nitric oxide (nNO) and fractional exhaled nitric oxide (FeNO) concentrations in children with sleep-disordered breathing (SDB).MethodsEnrolled inExpand
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Wnt/Planar Cell Polarity Signaling Controls the Anterior–Posterior Organization of Monoaminergic Axons in the Brainstem
Monoaminergic neurons [serotonergic (5-HT) and dopaminergic (mdDA)] in the brainstem project axons along the anterior–posterior axis. Despite their important physiological functions and implicationExpand
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Neuropilin-2 Regulates the Development of Select Cranial and Sensory Nerves and Hippocampal Mossy Fiber Projections
Neuropilin-1 and neuropilin-2 bind differentially to different class 3 semaphorins and are thought to provide the ligand-binding moieties in receptor complexes mediating repulsive responses to theseExpand
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