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- Publications
- Influence
Synthesis of 2,3-dihydro-3-hydroxy-2-hydroxylalkylbenzofurans from epoxy aldehydes. One-step syntheses of brosimacutin G, vaginidiol, vaginol, smyrindiol, xanthoarnol, and Avicenol A. Biomimetic…
We have developed two practical one-step syntheses of 2,3-dihydro-3-hydroxy-2-hydroxyalkylbenzofurans from readily available optically pure alpha,beta-epoxy aldehydes. Electron-deficient resorcinols… Expand
Synthesis of the carbocyclic skeleton of abyssomicins C and D.
[reaction: see text] Intramolecular Diels-Alder substrate trienyl methylenebutenolide 5 was prepared in six steps by coupling 3-methoxy-4-methylenebutenolide (6) with trienone keto aldehyde 7.… Expand
Discovery of 5-(3,4-Difluorophenyl)-3-(pyrazol-4-yl)-7-azaindole (GNF3809) for β-Cell Survival in Type 1 Diabetes
- Zhihong Huang, M. Tremblay, +17 authors Y. Liu
- Chemistry
- 18 February 2019
Pancreatic β-cell apoptosis, a hallmark of the development of type 1 diabetes (T1D), is associated with increased levels of pro-inflammatory cytokines. Thus, an agent protecting β-cells from… Expand
Formal synthesis of (+/-)-platensimycin.
- Y. Zou, Chun-Hsing Chen, C. Taylor, B. M. Foxman, B. Snider
- Chemistry, Medicine
- Organic letters
- 26 April 2007
[reaction: see text] Reductive alkylation of 5-methoxy-1-tetralone (6) with 2,3-dibromopropene gave an equilibrium mixture of bicyclic diones 7 (51%) and 8 (35%). Radical cyclization of 7 afforded… Expand
Photocatalytic degradation of aqueous 4-chlorophenol by silica-immobilized polyoxometalates.
- B. Yue, Y. Zhou, +4 authors Songlin Jin
- Chemistry, Medicine
- Environmental science & technology
- 9 February 2002
The degradation of 4-chlorophenol with near-UV light by silica-immobilized polyoxometalate (POM-in-SiO2) catalysts has been studied. The silica-immobilized Na6W7O24 (SW7), H4W1032 (SW10), H3PW12O40… Expand
Total synthesis of (+/-)-symbioimine.
The synthesis of (±)-symbioimine (1) has been completed in only 12 linear steps in 8% overall yield. The key step is the treatment of 13b with BF3·Et2O to generate N-carboalkoxydihydropyridinium… Expand
Synthesis of the Carbocyclic Skeleton of Abyssomicins C and D.
- B. B. Snider, Y. Zou
- Chemistry
- 7 March 2006
Syntheses of brosimacutin G, vaginidiol, vaginol, smyrindiol, xanthoarnol, avicenol A, angelicin, psoralen, symbioimine, and the carbocyclic skeleton of abyssomicins C and D. Formal synthesis of…
- Yefen Zou
- Chemistry
- 2007
Compounds 6-6 fused bicyclic heteroaryl and their use as inhibitors of LVL
- Jianfeng Pan, Tingting Mo, +14 authors Shanshan Yan
- Chemistry
- 25 October 2019
The present invention relates to bicyclic heteroaryl compounds of Formula 6-6 fused or A1 A2 and their use as inhibitors of LATS, or a salt, a stereoisomer or a pharmaceutical composition of these… Expand
Total synthesis of (+/-)-symbioimine.
The synthesis of (+/-)-symbioimine (1) has been completed in only 12 linear steps in 8% overall yield. The key step is the treatment of 13b with BF3.Et2O to generate N-carboalkoxydihydropyridinium… Expand