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- Publications
- Influence
Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes
- Y. Zhu, C. D. Rice, Y. Pang, M. Pace, P. Thomas
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 6 February 2003
The structures of membrane receptors mediating rapid, nongenomic actions of steroids have not been identified. We describe the cloning of a cDNA from spotted seatrout ovaries encoding a protein that… Expand
Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor
- Y. Zhu, J. Bond, P. Thomas
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 24 February 2003
Recently we discovered a previously uncharacterized gene with the characteristics of a membrane progestin receptor (mPR) in a fish model, spotted seatrout. Here, we report the identification,… Expand
A Draft Sequence for the Genome of the Domesticated Silkworm (Bombyx mori)
We report a draft sequence for the genome of the domesticated silkworm (Bombyx mori), covering 90.9% of all known silkworm genes. Our estimated gene count is 18,510, which exceeds the 13,379 genes… Expand
microRNA miR-196a-2 and breast cancer: a genetic and epigenetic association study and functional analysis.
- A. Hoffman, T. Zheng, +6 authors Y. Zhu
- Biology, Medicine
- Cancer research
- 15 July 2009
Increasing evidence has suggested that microRNAs (miRNA) play an important role in tumorigenesis. As transcriptional regulators, altered miRNA expression may affect many cancer-related biological… Expand
Telomere dysfunction: a potential cancer predisposition factor.
BACKGROUND
Genetic instability associated with telomere dysfunction (i.e., short telomeres) is an early event in tumorigenesis. We investigated the association between telomere length and cancer risk… Expand
CLOCK in breast tumorigenesis: genetic, epigenetic, and transcriptional profiling analyses.
- A. Hoffman, Chunhui Yi, +7 authors Y. Zhu
- Biology, Medicine
- Cancer research
- 15 February 2010
The transcription factors responsible for maintaining circadian rhythm influence a variety of biological processes. Recently, it has been suggested that the core circadian genes may play a role in… Expand
Evaluation of genetic variants in microRNA-related genes and risk of bladder cancer.
MicroRNAs (miRNA) are small noncoding RNA molecules involved in a diversity of cellular functions. Although it has been reported that global suppression of the miRNA biogenesis pathway leads to… Expand
Altruism and social cheating in the social amoeba Dictyostelium discoideum
- J. Strassmann, Y. Zhu, D. Queller
- Biology, Medicine
- Nature
- 21 December 2000
The social amoeba, Dictyostelium discoideum, is widely used as a simple model organism for multicellular development, but its multicellular fruiting stage is really a society. Most of the time, D.… Expand
Changing incidence of thyroid cancer.
To the Editor: In their study of the increasing incidence of thyroid cancer in the United States between 1973 and 2002, Drs Davies and Welch concluded that the increase was artifactual, due to… Expand
A Phylogenetic Perspective on Sequence Evolution in Microsatellite Loci
- Y. Zhu, D. Queller, J. Strassmann
- Biology, Medicine
- Journal of Molecular Evolution
- 1 April 2000
Abstract. We examined the evolution of the repeat regions of three noncoding microsatellite loci in 58 species of the Polistinae, a subfamily of wasps that diverged over 140 million years ago. A… Expand
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