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Identification of genomic alterations in oesophageal squamous cell cancer
Oesophageal cancer is one of the most aggressive cancers and is the sixth leading cause of cancer death worldwide. Approximately 70% of global oesophageal cancer cases occur in China, with… Expand
The China National Stroke Registry for Patients with Acute Cerebrovascular Events: Design, Rationale, and Baseline Patient Characteristics
- Yongjun Wang, L. Cui, +11 authors H. Li
- International journal of stroke : official…
- 1 August 2011
Background As a leading cause of severe disability and death, stroke places an enormous burden on the health care system in China. There are limited data on the pattern of current medical practice… Expand
miR‐329 suppresses the growth and motility of neuroblastoma by targeting KDM1A
- Haifeng Yang, Q. Li, Wohua Zhao, Dun Yuan, H. Zhao, Y. Zhou
- Biology, Medicine
- FEBS letters
- 3 January 2014
MicroRNAs (miRNAs) act as key regulators of multiple cancers. miR‐329 functions as a tumor suppressor in some malignancies. However, its role in neuroblastoma remains poorly understood. We found that… Expand
Association of Systemic Lupus Erythematosus With Decreased Immunosuppressive Potential of the IgG Glycome
- F. Vučković, Jasminka Krištić, +25 authors G. Lauc
- Medicine, Biology
- Arthritis & rheumatology
- 1 July 2015
Glycans attached to the Fc portion of IgG are important modulators of IgG effector functions. Interindividual differences in IgG glycome composition are large and they associate strongly with… Expand
Gold nanorod-based localized surface plasmon resonance biosensor for sensitive detection of hepatitis B virus in buffer, blood serum and plasma.
- Xiaohui Wang, Y. Li, +6 authors Linsheng Zhan
- Chemistry, Medicine
- Biosensors & bioelectronics
- 15 October 2010
A novel gold nanorods (GNRs) biosensor based on the localized surface plasmon resonance (LSPR) behavior was designed to detect the hepatitis B surface antigen (HBsAg) which indicates active viral… Expand
Progesterone-induced activation of membrane-bound progesterone receptors in murine macrophage cells.
Parturition is an inflammatory process mediated to a significant extent by macrophages. Progesterone (P4) maintains uterine quiescence in pregnancy, and a proposed functional withdrawal of P4… Expand
Inhibition of Acid Sphingomyelinase Depletes Cellular Phosphatidylserine and Mislocalizes K-Ras from the Plasma Membrane
- K. Cho, Dharini van der Hoeven, +5 authors J. Hancock
- Biology, Medicine
- Molecular and Cellular Biology
- 16 November 2015
ABSTRACT K-Ras must localize to the plasma membrane for biological activity; thus, preventing plasma membrane interaction blocks K-Ras signal output. Here we show that inhibition of acid… Expand
A prospective cohort study of lesion location and its relation to post-stroke depression among Chinese patients.
BACKGROUND Post-stroke depression (PSD) is a common consequence of stroke that negatively interferes with the rehabilitation outcome in patients. It remains unclear what relationship exists between… Expand
miR-96 promotes cell proliferation, migration and invasion by targeting PTPN9 in breast cancer
microRNAs (miRNAs) have emerged as major regulators of the initiation and progression of human cancers, including breast cancer. The aim of this study is to determine the expression pattern of miR-96… Expand
Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability.
Gastric cancer is not a single disease, and its subtype classification is still evolving. Next-generation sequencing studies have identified novel genetic drivers of gastric cancer, but their use as… Expand