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Molecular Epidemiology of Clostridium difficile Infection in Hospitalized Patients in Eastern China
TLDR
Among risk factors for CDI, the advanced age threshold was younger for Chinese patients than that reported for patients in developed countries and is clearly a problem in eastern China. Expand
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) Protein Inhibits Type I and III Interferon Production by Targeting RIG-I/MDA-5 Signaling
TLDR
Insight is provided into the interpretation of the SARS-CoV-2-induced antiviral immune suppression and sheds light on the pathogenic mechanism of COVID-19. Expand
Small-Molecule Targeting of Proliferating Cell Nuclear Antigen Chromatin Association Inhibits Tumor Cell Growth
TLDR
A class of compounds that can directly bind to PCNA, stabilize PCNA trimers, reduce PCNA association with chromatin, and inhibit tumor cell growth by inducing a cell cycle arrest are identified. Expand
Novel Risk Loci for Rheumatoid Arthritis in Han Chinese and Congruence With Risk Variants in Europeans
TLDR
To investigate differences in genetic risk factors for rheumatoid arthritis (RA) in Han Chinese as compared with Europeans, a genome-wide association study was conducted. Expand
The use of gadolinium-carbon nanostructures to magnetically enhance stem cell retention for cellular cardiomyoplasty.
TLDR
These proof-of-concept studies support the feasibility and value of using GNTs as a magnetic nanoparticle facilitator to improve cell retention during cellular cardiomyoplasty. Expand
Quantification of liver viscoelasticity with acoustic radiation force: a study of hepatic fibrosis in a rat model.
TLDR
The study finds that although viscosity is not as good as elasticity for staging fibrosis, it is important to consider viscoelasticity to make an accurate estimation of elasticity; it may also provide other mechanical insights into liver tissues. Expand
Penehyclidine hydrochloride ameliorates renal ischemia-reperfusion injury in rats.
TLDR
Penehyclidine hydrochloride protected rat kidneys from I/R injury by attenuating oxidative stress, inflammatory response, and apoptosis and may represent a novel practical strategy for the treatment of renal I-R injury. Expand
Epidemiological and clinical characteristics analysis of COVID-19 in the surrounding areas of Wuhan, Hubei Province in 2020
TLDR
No evidence exists that smoking protects COVID-19 patients from developing to severe/critical cases, and the absolute number of lymphocytes at initial diagnosis could not predict the progression risk from severe to critical condition. Expand
Mental health services for children in China during the COVID-19 pandemic: results of an expert-based national survey among child and adolescent psychiatric hospitals
TLDR
A survey on the situation of hospitals which provide mental health services for children in China and experts’ suggestions for mental health care of children during the COVID-19 pandemic were collected. Expand
Prevalence of Anxiety and Associated Factors for Chinese Adolescents during the COVID‐19 Outbreak
TLDR
This is the first study presenting information about the mental health status of Ecuadorians in epidemiological surveillance during the pandemic, however, the data did not confirm that the presence of psychological symptoms was a product of being under surveillance. Expand
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