• Publications
  • Influence
MEK/ERK signaling contributes to the maintenance of human embryonic stem cell self-renewal.
MEK/ERK signaling plays a crucial role in a diverse set of cellular functions including cell proliferation, differentiation and survival, and recently has been reported to negatively regulate mouseExpand
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Social Influence Bias : A Randomized Experiment
vidually minor compounds is important. Future research is required to determine if this is also true for ecosystems that emit larger quantities of isoprene and/or monoterpenes. The minor species withExpand
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ABA receptor PYL9 promotes drought resistance and leaf senescence
Significance We identified transgenic plants that are extremely resistant to drought from a large-scale screening of transgenic plants overexpressing the pyrabactin resistance 1-like (PYL) family ofExpand
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Two supporting factors greatly improve the efficiency of human iPSC generation.
Summary Human fibroblasts can be induced into pluripotent stem cells (iPSCs), but the reprogramming efficiency is quite low. Here, we screened a panel of candidate factors in the presence of OCT4 ,Expand
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Nitrogen-doped graphene quantum dots with oxygen-rich functional groups.
  • Y. Li, Y. Zhao, +4 authors L. Qu
  • Chemistry, Medicine
  • Journal of the American Chemical Society
  • 11 January 2012
Graphene quantum dots (GQDs) represent a new class of quantum dots with unique properties. Doping GQDs with heteroatoms provides an attractive means of effectively tuning their intrinsic propertiesExpand
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Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo.
We used a multifunctional mesoporous silica nanoparticle (MSNP) carrier to overcome doxorubicin (Dox) resistance in a multidrug resistant (MDR) human breast cancer xenograft by codelivering Dox andExpand
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Comparative analysis of oncogenic genes revealed unique evolutionary features of field Marek's disease virus prevalent in recent years in China
BackgroundMarek's disease (MD) is an economically important viral disease of chickens caused by Marek's disease virus (MDV), an oncogenic herpesvirus. This disease was well controlled since theExpand
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Functional specialization of β-arrestin interactions revealed by proteomic analysis
β-arrestins are cytosolic proteins that form complexes with seven-transmembrane receptors after agonist stimulation and phosphorylation by the G protein-coupled receptor kinases. They play anExpand
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Noggin and bFGF cooperate to maintain the pluripotency of human embryonic stem cells in the absence of feeder layers.
Human embryonic stem (hES) cells are typically maintained on mouse embryonic fibroblast (MEF) feeders or with MEF-conditioned medium. However, these xenosupport systems greatly limit the therapeuticExpand
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Integrated control-path design and error recovery in the synthesis of digital microfluidic lab-on-chip
TLDR
We present a synthesis method that incorporates control paths and an error-recovery mechanism in the design of a digital microfluidic lab-on-chip that reduces the completion time by 30% when errors occur during the implementation of the bioassay. Expand
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