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Bayesian inference of epistatic interactions in case-control studies
Epistatic interactions among multiple genetic variants in the human genome may be important in determining individual susceptibility to common diseases. Although some existing computational methods… Expand
Alignment of Optical Maps
- Anton Valouev, Lei Li, +4 authors M. Waterman
- Mathematics, Computer Science
- J. Comput. Biol.
- 1 March 2006
We introduce a new scoring method for calculation of alignments of optical maps. Expand
Jointly characterizing epigenetic dynamics across multiple human cell types
Advanced sequencing technologies have generated a plethora of data for many chromatin marks in multiple tissues and cell types, yet there is lack of a generalized tool for optimal utility of those… Expand
A novel bayesian graphical model for genome‐wide multi‐SNP association mapping
- Y. Zhang
- Biology, Medicine
- Genetic epidemiology
- 1 January 2012
Most disease association mapping algorithms are based on hypothesis testing procedures that test one variant at a time. Those methods lose power when the disease mutations are jointly tagged by… Expand
Macular and peripapillary retinal nerve fiber layer thickness in children with hyperopic anisometropic amblyopia.
- Shuangqing Wu, L. Zhu, Qi-bin Xu, Jun-Li Xu, Y. Zhang
- International journal of ophthalmology
AIM To compare the retinal nerve fiber layer (RNFL) thickness and macular thickness in the amblyopic eye with that in the sound eye of children with hyperopic anisometropic amblyopia using optical… Expand
Accurate and reproducible functional maps in 127 human cell types via 2D genome segmentation
Abstract The Roadmap Epigenomics Consortium has published whole-genome functional annotation maps in 127 human cell types by integrating data from studies of multiple epigenetic marks. These maps… Expand
Effect of Triton X-100 on the removal of aqueous phenol by laccase analyzed with a combined approach of experiments and molecular docking.
- Y. Zhang, Zhuotong Zeng, +6 authors G. Xie
- Chemistry, Medicine
- Colloids and surfaces. B, Biointerfaces
- 1 September 2012
Effects of Triton X-100 on the removal of aqueous phenol catalyzed by laccase were studied. The optimal concentration of Triton X-100 was 155 μM to improve phenol removal when the concentrations of… Expand
Bayesian Models for Detecting Epistatic Interactions from Genetic Data
Current disease association studies are routinely conducted on a genome‐wide scale, testing hundreds of thousands or millions of genetic markers. Besides detecting marginal associations of individual… Expand
Orthogonal array deciphering MRS medium requirements for isolated Lactobacillus rhamnosus ZY with cell properties characterization.
- Y. Zhang, I. Ng, Chuanyi Yao, Y. Lu
- Chemistry, Medicine
- Journal of bioscience and bioengineering
- 1 September 2014
Lactobacillus rhamnosus is a well-known lactic acid bacterium (LAB), but a new ZY strain was isolated for the first time from commercial probiotic powder recently. Although many studies have focused… Expand
Progress in genetic improvement of grain yield and related physiological traits of Chinese wheat in Henan Province
Abstract Wheat is one of the staple food crops worldwide and breeding for high yield wheat is critical to meet the need of increasing world population. To determine the factors that limit wheat yield… Expand