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A linking function for the cellulose-binding protein SP85 in the spore coat of Dictyostelium discoideum.
SP85 is a multidomain protein of the Dictyostelium spore coat whose C-terminal region binds cellulose in vitro. To map domains critical for localizing SP85 and for binding to other proteins in vivo,Expand
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Antisense inhibition of beta(1)-adrenergic receptor mRNA in a single dose produces a profound and prolonged reduction in high blood pressure in spontaneously hypertensive rats.
BACKGROUND beta-Blockers are the first line of therapy for hypertension. However, they are associated with side effects because of central nervous system (CNS) effects and beta(2)-adrenergicExpand
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A CapG gain‐of‐function mutant reveals critical structural and functional determinants for actin filament severing
CapG is the only member of the gelsolin family unable to sever actin filaments. Changing amino acids 84–91 (severing domain) and 124–137 (WH2‐containing segment) simultaneously to the sequences ofExpand
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MiR-15b-5p is Involved in Doxorubicin-Induced Cardiotoxicity via Inhibiting Bmpr1a Signal in H9c2 Cardiomyocyte
The wide use of anthracyclines represented by doxorubicin (DOX) has benefited cancer patients, yet the clinical application is limited due to its cardiotoxicity. Although numerous evidences haveExpand
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Explicit piecewise smooth solutions of Landau-Lifshitz equation with discontinuous external field
In this paper, we shall construct some explicit piecewise smooth (global continuous) solutions as well as blow up solutions to the multidimensional Landau-Lifshitz equation, subject to the externalExpand
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Two proteins of the Dictyostelium spore coat bind to cellulose in vitro.
The spore coat of Dictyostelium contains nine different proteins and cellulose. Interactions between protein and cellulose were investigated using an in vitro binding assay. Proteins extracted fromExpand
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Intravenous angiotensinogen antisense in AAV-based vector decreases hypertension.
Angiotensinogen (AGT) has been linked to hypertension. Because there are no direct inhibitors of AGT, we have developed antisense (AS) inhibition of AGT mRNA delivered in an adeno-associated virusExpand
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Observation of locomotor functional recovery in adult complete spinal rats with BWSTT using semiquantitative and qualitative methods
Study design:Experimental rat model of spinal cord transection.Setting:China rehabilitation research center.Objective:To investigate locomotor functional recovery in spinal rats with BWSTT usingExpand
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Gene Therapy for Hypertension: Recombinant Adeno-Associated Virus Vector Delivery of Angiotensin Type 1 Receptor Antisense in Hypertensive Double Transgenic Mice
P204 Introduction: The goal of gene therapy for hypertension is to produce prolonged reductions of high blood pressure with a single administration of a transgene. We have developed gene therapyExpand
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Genomic identification, phylogeny, and expression analysis of MLO genes involved in susceptibility to powdery mildew in Fragaria vesca.
The MLO (powdery mildew locus O) gene family is important in resistance to powdery mildew (PM). In this study, all of the members of the MLO family were identified and analyzed in the strawberryExpand
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