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In vitro biological effects of volcanic ash from Mount Sakurajima.
The ash did not inhibit the colony formation of V79-4 cells and failed to activate complement or generate chemotactic factor activity in samples of fresh human serum, and was minimally active in causing the release of lysosomal enzymes from human neutrophile. Expand
Lack of gene deletion for complement C4A deficiency in Japanese patients with systemic lupus erythematosus.
The results indicate that C4AQ0 may contribute to the pathogenesis of SLE beyond the ethnical differences but Japanese patients with SLE have a different genetic background from Caucasian patients with the C 4A gene deleted. Expand
Serum complement changes in W/Fu rats inoculated with syngeneic (C58NT) D lymphoma cells.
Moderate to marked depressions of overall hemolytic activity, C1, C3 and properdin were observed in uninjected W/Fu rats or in animals inoculated with syngeneic normal spleen cells, and factor B levels were also depressed. Expand
Activation of the alternative (properdin) pathway by divalent cations.
Mg++, Mn++ and Co++ activate the C system as judged by the reduction in cobra venom factor indeed hemolysis, and cleavage of properdin factor B and C3. The maximum effect requires the addition of 5Expand
The change in C3b receptors on erythrocytes from patients with systemic lupus erythematosus.
A functional assay to quantify the amount of CR1 showed a decrease in erythrocytes from patients with SLE, rheumatoid arthritis and other connective tissue diseases, implying that the reduction of CR 1 found in SLE patients might be cause not only by hereditary factors but by unknown factors that influence the amount or function ofCR1. Expand
Quantification of the complement receptor function on polymorphonuclear leukocytes: its significance in patients with systemic lupus erythematosus.
The function of complement receptors (CR1) on polymorphonuclear leukocytes (PMN) was assessed by C3b mediated binding of immune complexes (IC) to PMN and was reduced compared with those from normal controls or patients with rheumatoid arthritis. Expand
Restriction fragment length polymorphism of complement C4 in Japanese patients with rheumatoid arthritis and normal Japanes
Restriction fragment length polymorphism (RFLP) of the two genes for complement C4A and C4B was studied in 56 Japanese patients with rheumatoid arthritis and 161 normal individuals to deduce three common RFLP-types. Expand
Interaction between immune complexes and C3b receptors on erythrocytes.
A dynamic in vivo interaction between IC and CR1 on E which are supposed to transport IC to the reticuloendothelial system is suggested which might make IC less harmful to the tissues in the process of releasing IC from E. Expand
Correlation between the atmospheric conditions and the asthmatic symptom
A point process model was used for analysis of the correlation between the state of the atmosphere and the presence or absence of asthmatic symptom known from diaries in which a day was divided into four parts. Expand