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[Effects of Lycium barbarum polysaccharide on tumor microenvironment T-lymphocyte subsets and dendritic cells in H22-bearing mice].
- Yan-Li He, Y. Ying, Yan-li Xu, Jun-Fang Su, Hui Luo, Hui-Feng Wang
- BiologyZhong xi yi jie he xue bao = Journal of Chinese…
- 1 September 2005
LBP has anti-tumor effect probably by increasing the numbers of CD4(+) and CD8(+) T cells in TIL to relieve the immunosuppression and enhance the anti-Tumor function of the immune system.
miR-196b/miR-1290 participate in the antitumor effect of resveratrol via regulation of IGFBP3 expression in acute lymphoblastic leukemia.
Evidence is provided that resveratrol targets miR-196b andmiR-1290 for its antitumor activity in T-ALL and B-ALL, respectively and also confirms that both miR‑ 196b and miR -1290 target the IGFBP3 3'-UTR and are potential therapeutic targets for ALL.
MicroRNA-148b enhances the radiosensitivity of non-Hodgkin's Lymphoma cells by promoting radiation-induced apoptosis
Results demonstrate that miR-148b increased the radiosensitivity of NHL cells probably by promoting radiation-induced apoptosis, which suggests thatMiR- 148b plays an important role in the response of NHL to ionizing radiation.
miR-196 b / miR-1290 participate in the antitumor effect of resveratrol via regulation of IGFBP 3 expression in acute lymphoblastic leukemia
Evidence is provided that resveratrol targets miR196b and miR-1290 for its antitumor activity in T-ALL and B-ALL, respectively and targets the IGFBP3 3'-UTR and are potential therapeutic targets for ALL.
Identification of microRNAs involved in gefitinib resistance of non-small-cell lung cancer through the insulin-like growth factor receptor 1 signaling pathway
- Wei-Qing Ma, Yanhong Kang, Lanlan Ning, Jie Tan, Hanping Wang, Y. Ying
- BiologyExperimental and therapeutic medicine
- 28 July 2017
The results suggest that a number of miRNAs associated with the IGF-1R signaling pathway, including miR-497-3p andmiR-144-5p, were involved in the development of resistance against EGFR-TKIs in A549 cells.
Sustained and stable hematopoietic donor‐recipient mixed chimerism after unrelated cord blood transplantation for adult patients with severe aplastic anemia
This study shows that durable donor‐recipient stable mixed chimerism can be achieved by unrelated CBSCT in patients with SAA, and Umbilical cord blood could be employed as a source of hematopoietic stem cell for adult transplantation.
Umbilical cord blood transplant for adult patients with severe aplastic anemia using anti-lymphocyte globulin and cyclophosphamide as conditioning therapy
Allo-CBSCT (cord blood stem cell transplant) has been applied in six adult patients with severe aplastic anemia (SAA) and four patients are alive and disease free after a median follow up of 20 months.
Calibration of interphase fluorescence in situ hybridization cutoff by mathematical models
- Q. Du, Qingshan Li, Daochun Sun, Xiao-yan Chen, Bizhen Yu, Y. Ying
- BiologyCytometry. Part A : the journal of the…
- 1 March 2016
Two probability models can be used to assess the effect of signal overlap and calibrate the cutoff, and the dynamic cutoff can classify cases in routine analysis correctly and correct for influences from nuclei area and the number of signals in some ambiguous cases.
Umbilical cord blood transplantation from unrelated HLA-matched donor in an adult with severe aplastic anemia
Microsatellite DNA fingerprinting indicated a stable and persistent donor–recipient mixed chimerism, whilst the circulating red cells remain of host origin.
Resveratrol Suppresses Growth and Migration of Myelodysplastic Cells by Inhibiting the Expression of Elevated Cyclin D1 (CCND1).
- Wei Zhou, Shi-lin Xu, Y. Ying, Ruiqing Zhou, Xiao-wei Chen
- BiologyDNA and cell biology
- 1 November 2017
It is proved that resveratrol suppresses SKM-1 growth and migration by inhibiting CCND1 expression, which provides novel insights into the pathogenesis of MDS and might help develop new diagnosis and treatment for patients with MDS.