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Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine.
S-1 is an effective adjuvant treatment for East Asian patients who have undergone a D2 dissection for locally advanced gastric cancer and has a higher rate of overall survival than the surgery-only group.
S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial.
Gastric cancer surgery: morbidity and mortality results from a prospective randomized controlled trial comparing D2 and extended para-aortic lymphadenectomy--Japan Clinical Oncology Group study 9501.
Specialized surgeons could safely perform gastrectomy with D2 lymphadenectomy with para-aortic nodal dissection in patients with low operative risks without increasing major surgical complications in this setting.
D2 lymphadenectomy alone or with para-aortic nodal dissection for gastric cancer.
Treatment with D2 lymphadenectomy plus PAND does not improve the survival rate in curable gastric cancer, and no significant differences in recurrence-free survival are found.
Clinical practice guidelines for gastrointestinal stromal tumor (GIST) in Japan: English version
The English version of the Japanese Clinical Practice Guideline for GIST is presented, prepared by the GIST Guideline Subcommittee, and was published after assessment by the Guideline Evaluation Committee of JSCO.
NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism and the risk of eight cancers for Japanese
- N. Hamajima, K. Matsuo, K. Tajima
- Medicine, BiologyInternational Journal of Clinical Oncology
- 1 April 2002
This study suggests that the CC genotype of the NQO1 C609T polymorphism is associated with the risk of lung cancer, and that the TT genotype increases therisk of smoking for cancers of the esophagus and lung.
Association of prostate stem cell antigen gene polymorphisms with the risk of stomach cancer in Japanese
PSCA polymorphisms are associated with stomach cancer risk in Japanese and a possible interaction with family history warrants further evaluation.
Survival After Curative Resection for Mucinous Adenocarcinoma of the Colorectum
There was significant correlation with prognosis as measured by overall survival rate after adjustment had been made for major confounders, and the mucinous histologic type itself was an independent factor for poor prognosis for patients who underwent curative surgery.
No associations of p73 G4C14-to-A4T14 at exon 2 and p53 Arg72Pro polymorphisms with the risk of digestive tract cancers in Japanese.
Effects of Dietary, Drinking, and Smoking Habits on the Prognosis of Gastric Cancer
It is suggested that frequent intake of raw vegetables and tofu is favorable, whereas habitual smoking is an adverse prognostic factor for gastric cancer.