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Evidence for a role of developmental genes in the origin of obesity and body fat distribution.
Obesity, especially central obesity, is a hereditable trait associated with a high risk for development of diabetes and metabolic disorders. Combined gene expression analysis of adipocyte- andExpand
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New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
Adipose tissue is central to the regulation of energy balance. Two functionally different types of fat are present in mammals: white adipose tissue, the primary site of triglyceride storage, andExpand
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New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
This corrects the article DOI: 10.1038/nature07221
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E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition
E7080 is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors. In this study, we show the inhibitory activity of E7080 against SCF‐inducedExpand
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Birth of parthenogenetic mice that can develop to adulthood
Only mammals have relinquished parthenogenesis, a means of producing descendants solely from maternal germ cells. Mouse parthenogenetic embryos die by day 10 of gestation. Bi-parental reproduction isExpand
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Beneficial effects of subcutaneous fat transplantation on metabolism.
Subcutaneous (SC) and visceral (VIS) obesity are associated with different risks of diabetes and the metabolic syndrome. To elucidate whether these differences are due to anatomic location orExpand
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Knee Stability and Graft Function after Anterior Cruciate Ligament Reconstruction
Background Locations of femoral tunnels for anterior cruciate ligament replacement grafts remain a subject of debate. Hypothesis A lateral femoral tunnel placed at the insertion of the posterolateralExpand
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An iron-binding protein, Dpr, from Streptococcus mutans prevents iron-dependent hydroxyl radical formation in vitro.
The dpr gene is an antioxidant gene which was isolated from the Streptococcus mutans chromosome by its ability to complement an alkyl hydroperoxide reductase-deficient mutant of Escherichia coli, andExpand
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Osteochondral Autograft Transplantation for Osteochondritis Dissecans of the Elbow in Juvenile Baseball Players
Background Osteochondral autografts have recently become popular to treat articular cartilage defects, and they are used for unstable osteochondritis dissecans lesions as a means of biologicalExpand
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A 0.13µm SiGe BiCMOS technology featuring fT/fmax of 240/330 GHz and gate delays below 3 ps
A 0.13 µm SiGe BiCMOS technology for millimeter wave applications is presented. Expand
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