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- Publications
- Influence
Correlation of dietary aflatoxin B1 levels with excretion of aflatoxin M1 in human urine.
Corn and peanut oil (total, 253 samples) were collected from 32 households in Fushui county of the Guangxi autonomous region of the People's Republic of China, where high liver cancer incidence has… Expand
Spontaneous and radiation-induced chromosomal breakage at interstitial telomeric sites
- P. Slijepcevic, Y. Xiao, I. Domínguez, A. T. Natarajan
- Biology, Medicine
- Chromosoma
- 1 June 1996
The Chinese hamster genome contains a total of 18 cytologically detectable arrays of interstitial telometic sequences. A combination of G-banding and twocolour fluorescence in situ hybridization… Expand
Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction.
Fanconi anemia is a cancer-prone inherited bone marrow failure and cancer susceptibility syndrome with at least 13 complementation groups (FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG,… Expand
Induction and persistence of chromosomal exchanges in mouse bone marrow cells following whole-body exposure to X-rays.
- Y. Xiao, F. Darroudi, M. Grigorova, A. T. Natarajan
- Biology, Medicine
- International journal of radiation biology
- 1 September 1999
PURPOSE
To investigate the induction and persistence of chromosome aberrations in mouse bone marrow cells after X-ray exposure and to detect differential involvement of individual chromosomes in… Expand
Analysis of micronuclei induced by 1,3-butadiene and its metabolites using fluorescence in situ hybridization.
- Y. Xiao, J. de Stoppelaar, B. Hoebee, G. Schriever-Schwemmer, I. Adler, A. Tates
- Biology, Medicine
- Mutation research
- 5 July 1996
In our previous study, micronuclei (MN) were induced in bone marrow cells of mice following inhalation exposure to 1300 ppm of 1,3-butadiene (BD) for 6 h per day on 5 consecutive days, and in… Expand
Frequencies and types of exchange aberrations induced by X-rays and neutrons in Chinese hamster splenocytes detected by FISH using chromosome-specific DNA libraries.
- M. Grigorova, R. Brand, Y. Xiao, A. T. Natarajan
- Biology, Medicine
- International journal of radiation biology
- 1998
PURPOSE
To estimate the frequencies of radiation- (low and high LET) induced chromosome aberrations in Chinese hamster splenocytes by two-colour fluorescence in situ hybridization using DNA painting… Expand
Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance.
- J. B. Wilson, E. Blom, R. Cunningham, Y. Xiao, G. Kupfer, N. Jones
- Biology, Medicine
- Mutation research
- 7 July 2010
The Fanconi anaemia (FA) FANCG protein is an integral component of the FA nuclear core complex that is required for monoubiquitylation of FANCD2. FANCG is also part of another protein complex termed… Expand
Mechanisms of induction of chromosomal aberrations and their detection by fluorescence in situ hybridization.
- A. T. Natarajan, A. Balajee, +7 authors Y. Xiao
- Biology, Medicine
- Mutation research
- 1 December 1996
Fluorescence in situ hybridization (FISH) technique using chromosome specific probes has revolutionized the field of radiation cytogenetics in the last few years. Some of the new insights on the… Expand
Development of DNA libraries specific for Chinese hamster chromosomes 3, 4, 9, 10, X, and Y by DOP-PCR.
- Y. Xiao, P. Slijepcevic, G. Arkesteijn, F. Darroudi, A. T. Natarajan
- Biology, Medicine
- Cytogenetics and cell genetics
- 1 July 1996
In a previous study of ours, DNA libraries specific for Chinese hamster chromosomes 1, 2, 3, 5, 6, 7, and 8 were constructed by single laser flow sorting and the linker adapter PCR method. Since a… Expand
Clastogenic effects of 1, 3‐butadiene and its metabolites 1,2‐epoxybutene and 1,2,3,4‐diepoxybutane in splenocytes and germ cells of rats and mice in vivo
Clastogenicity of 1,3‐butadiene (BD), 1,2‐epoxybutene (EB), and 1,2,3,4‐diepoxybutane (DEB) was studied in splenocytes and germ cells of rats and mice by means of micronucleus assays… Expand