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[Insect antimicrobial peptides: structures, properties and gene regulation].
Insect antimicrobial peptides (AMPs) are an important group of insect innate immunity effectors. Insect AMPs are cationic and contain less than 100 amino acid residues. According to structure, insect… Expand
Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer
The tumor suppressor TP53 pathway plays a crucial role in preventing carcinogenesis through its ability to impose cell cycle arrest and apoptosis following DNA damage and oncogene activation. MDM2 is… Expand
ERK Inhibition Rescues Defects in Fate Specification of Nf1-Deficient Neural Progenitors and Brain Abnormalities
Germline mutations in the RAS/ERK signaling pathway underlie several related developmental disorders collectively termed neuro-cardio-facial-cutaneous (NCFC) syndromes. NCFC patients manifest varying… Expand
Whether sperm deoxyribonucleic acid fragmentation has an effect on pregnancy and miscarriage after in vitro fertilization/intracytoplasmic sperm injection: a systematic review and meta-analysis.
OBJECTIVE To examine whether sperm DNA fragmentation has an effect on pregnancy and miscarriage after IVF and/or intracytoplasmic sperm injection (ICSI). DESIGN Systematic review and meta-analysis.… Expand
An Ossified Meckel's Cartilage in Two Cretaceous Mammals and Origin of the Mammalian Middle Ear
An ossified Meckel's cartilage has been recovered from two early Cretaceous mammals from China. This element is similar to Meckel's cartilage in prenatal and some postnatal extant mammals and… Expand
Inflammation: The Common Pathway of Stress-Related Diseases
While modernization has dramatically increased lifespan, it has also witnessed that the nature of stress has changed dramatically. Chronic stress result failures of homeostasis thus lead to various… Expand
Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?
Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered in bone marrow, are multipotent cells capable of differentiating into mature cells of several mesenchymal… Expand
Gated tunability and hybridization of localized plasmons in nanostructured graphene.
- Zheyu Fang, S. Thongrattanasiri, +7 authors F. J. García de Abajo
- Materials Science, Medicine
- ACS nano
- 26 February 2013
Graphene has emerged as an outstanding material for optoelectronic applications due to its high electronic mobility and unique doping capabilities. Here we demonstrate electrical tunability and… Expand
Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility.
Matrix metalloproteinase-2 (MMP-2) plays important roles in cancer initiation and progression. Our previous studies revealed that the -1306C-->T and -735C-->T polymorphisms in MMP2 promoter… Expand
Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation
BackgroundDNA methylation is an important type of epigenetic modification involved in gene regulation. Although strong DNA methylation at promoters is widely recognized to be associated with… Expand