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- Publications
- Influence
Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics.
- D. Smith, L. Doucette-Stamm, +22 authors J. Reeve
- Medicine, Biology
- Journal of bacteriology
- 1 November 1997
The complete 1,751,377-bp sequence of the genome of the thermophilic archaeon Methanobacterium thermoautotrophicum deltaH has been determined by a whole-genome shotgun sequencing approach. A total of… Expand
The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells
In the developing cerebral cortex, neurons are born on a predictable schedule. Here we show in mice that the essential timing mechanism is programmed within individual progenitor cells, and its… Expand
Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal.
The embryonic stem cell (ESC) transcriptional and epigenetic networks are controlled by a multilayer regulatory circuitry, including core transcription factors (TFs), posttranscriptional modifier… Expand
NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17).
The Fc receptor CD16 is present on essentially all CD56(dim) peripheral blood natural killer (NK) cells. Upon recognition of antibody-coated cells it delivers a potent signal to NK cells, which… Expand
Endocannabinoids facilitate the induction of LTP in the hippocampus
- G. Carlson, Y. Wang, B. Alger
- Biology, Medicine
- Nature Neuroscience
- 1 August 2002
Exogenous cannabinoids disrupt behavioral learning and impede induction of long-term potentiation (LTP) in the hippocampus, yet endogenous cannabinoids (endocannabinoids) transiently suppress… Expand
Human mesenchymal stem cells stimulated by TNF-alpha, LPS, or hypoxia produce growth factors by an NF kappa B- but not JNK-dependent mechanism.
- Paul R. Crisostomo, Y. Wang, Troy A Markel, M. Wang, T. Lahm, D. Meldrum
- Biology, Medicine
- American journal of physiology. Cell physiology
- 1 March 2008
Understanding the mechanisms by which adult stem cells produce growth factors may represent an important way to optimize their beneficial paracrine and autocrine effects. Components of the wound… Expand
Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing.
- U. Kim, Y. Wang, T. Sanford, Y. Zeng, K. Nishikura
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 22 November 1994
We have cloned human cDNA encoding double-stranded RNA adenosine deaminase (DRADA). DRADA is a ubiquitous nuclear enzyme that converts multiple adenosines to inosines in double-helical RNA substrates… Expand
Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA.
Sunitinib resistance is a major challenge for advanced renal cell carcinoma (RCC). Understanding the underlying mechanisms and developing effective strategies against sunitinib resistance are highly… Expand
Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of ischemic preconditioning in conscious rabbits.
- K. Shinmura, X. Tang, +5 authors R. Bolli
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences…
- 29 August 2000
We examined the role of cyclooxygenase-2 (COX-2) in the late phase of ischemic preconditioning (PC). A total of 176 conscious rabbits were used. Ischemic PC (six cycles of 4-min coronary… Expand
Involvement of Notch signaling in hippocampal synaptic plasticity.
- Y. Wang, S. Chan, +5 authors K. Furukawa
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 22 June 2004
During development of the nervous system, the fate of stem cells is regulated by a cell surface receptor called Notch. Notch is also present in the adult mammalian brain; however, because Notch null… Expand