• Publications
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The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.
Skeletal development and turnover occur in close spatial and temporal association with angiogenesis. Osteoblasts are ideally situated in bone to sense oxygen tension and respond to hypoxia byExpand
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A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice
Resveratrol in high doses has been shown to extend lifespan in some studies in invertebrates and to prevent early mortality in mice fed a high-fat diet. We fed mice from middle age (14-months) to oldExpand
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Mutation Profiling in Cholangiocarcinoma: Prognostic and Therapeutic Implications
Background Cholangiocarcinoma (CCA) is clinically heterogeneous; intra and extrahepatic CCA have diverse clinical presentations. Next generation sequencing (NGS) technology may identify the geneticExpand
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Activated Neural Stem Cells Contribute to Stroke-Induced Neurogenesis and Neuroblast Migration toward the Infarct Boundary in Adult Rats
Stroke increases neurogenesis. The authors investigated whether neural stem cells or progenitor cells in the adult subventricular zone (SVZ) of rats contribute to stroke-induced increase inExpand
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The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT.
  • J. Wang, J. Lo, +6 authors Y. X. Fu
  • Medicine, Biology
  • The Journal of clinical investigation
  • 15 December 2001
Costimulatory molecules on antigen-presenting cells (APCs) play an important role in T cell activation and expansion. However, little is known about the surface molecules involved in direct T-T cellExpand
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Treatment of Stroke With Erythropoietin Enhances Neurogenesis and Angiogenesis and Improves Neurological Function in Rats
Background and Purpose— Erythropoietin (EPO) promotes proliferation and differentiation of erythroid progenitors and the survival of maturing erythroid cells. Here, we investigated the role of EPO inExpand
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Stromal cell-derived factor 1alpha mediates neural progenitor cell motility after focal cerebral ischemia.
In the adult rodent, stroke induces an increase in endogenous neural progenitor cell (NPC) proliferation in the subventricular zone (SVZ) and neuroblasts migrate towards the ischemic boundary. WeExpand
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Role of Toll-Like Receptor 4 in Endotoxin-Induced Acute Renal Failure 1
Toll-like receptor 4 (TLR4) is present on monocytes and other cell types, and mediates inflammatory events such as the release of TNF after exposure to LPS. C3H/HeJ mice are resistant to LPS-inducedExpand
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Analyses of CIA5, the master regulator of the carbon-concentrating mechanism in Chlamydomonas reinhardtii, and its control of gene expression
In numerous studies, the CIA5 gene of Chlamydomonas reinhardtii Dangeard has been shown to control the expression of several "CO2-responsive genes" when cells are shifted to higher or lower levels ofExpand
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A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats
The adult rodent brain is capable of generating neuronal progenitor cells in the subventricular zone, and in the dentate gyrus of the hippocampus, throughout the life of the animal. Signals thatExpand
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