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- Publications
- Influence
Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme.
- N. Shinojima, K. Tada, +10 authors Y. Ushio
- Medicine
- Cancer research
- 15 October 2003
Glioblastoma multiforme (GBM) frequently involves amplification and alteration of the epidermal growth factor receptor (EGFR) gene, resulting in overexpression of varied mutations, including the most… Expand
Usefulness of diffusion‐weighted MRI with echo‐planar technique in the evaluation of cellularity in gliomas
- T. Sugahara, Y. Korogi, +9 authors M. Takahashi
- Medicine
- Journal of magnetic resonance imaging : JMRI
- 1 January 1999
The purpose of this study was to evaluate the utility of diffusion‐weighted magnetic resonance imaging (MRI) with echo‐planar imaging (EPI) technique in depicting the tumor cellularity and grading of… Expand
Correlation of MR imaging-determined cerebral blood volume maps with histologic and angiographic determination of vascularity of gliomas.
- T. Sugahara, Y. Korogi, +8 authors M. Takahashi
- Medicine
- AJR. American journal of roentgenology
- 1 December 1998
OBJECTIVE
Our purpose was to evaluate the relationships between the ratio of maximum relative cerebral blood volume (rCBV) (rCBV ratio = rCBV[tumor]/rCBV[contralateral white matter]) and histologic… Expand
Posttherapeutic intraaxial brain tumor: the value of perfusion-sensitive contrast-enhanced MR imaging for differentiating tumor recurrence from nonneoplastic contrast-enhancing tissue.
- T. Sugahara, Y. Korogi, +6 authors M. Takahashi
- Medicine
- AJNR. American journal of neuroradiology
- 1 May 2000
BACKGROUND AND PURPOSE
Differentiation of tumor recurrence from treatment-related changes may be difficult with conventional MR imaging when newly enhancing lesions appear. Our aim was to determine… Expand
Activation of Akt/Protein Kinase B Contributes to Induction of Ischemic Tolerance in the CA1 Subfield of Gerbil Hippocampus
- S. Yano, M. Morioka, +6 authors Y. Ushio
- Medicine
- Journal of cerebral blood flow and metabolism…
- 1 April 2001
Apoptosis plays an important role in delayed neuronal cell death after cerebral ischemia. Activation of Akt/protein kinase B has been recently reported to prevent apoptosis in several cell types. In… Expand
Perfusion-sensitive MR imaging of gliomas: comparison between gradient-echo and spin-echo echo-planar imaging techniques.
- T. Sugahara, Y. Korogi, M. Kochi, Y. Ushio, M. Takahashi
- Medicine
- AJNR. American journal of neuroradiology
- 1 August 2001
BACKGROUND AND PURPOSE
The different sensitivities to vessel size of gradient-echo echo-planar imaging (GE-EPI) and spin-echo EPI (SE-EPI) might indicate the relative cerebral blood volumes (rCBVs)… Expand
Activation of Mitogen‐Activated Protein Kinase in Cultured Rat Hippocampal Neurons by Stimulation of Glutamate Receptors
- M. Kurino, K. Fukunaga, Y. Ushio, E. Miyamoto
- Biology, Medicine
- Journal of neurochemistry
- 1 September 1995
Abstract: Mitogen‐activated protein kinase (MAP kinase) was activated by stimulation of glutamate receptors in cultured rat hippocampal neurons. Ten micromolar glutamate maximally stimulated MAP… Expand
MR of epidermoids with a variety of pulse sequences.
- I. Ikushima, Y. Korogi, +6 authors Y. Ushio
- Medicine
- AJNR. American journal of neuroradiology
- 1 August 1997
PURPOSE
To assess the usefulness of fluid-attenuated inversion recovery (FLAIR) and constructive interference in steady state (CISS) sequences in depicting epidermoid tumors.
METHODS
Six patients… Expand
MRI of intracranial germ-cell tumours
Our aim was to review the MRI appearances of primary intracranial germ-cell tumours (GCT). We reviewed the MRI studies of 32 patients: 19 with germinomas, five with teratomas, one with an embryonal… Expand
Chemotherapy of brain metastases from lung carcinoma: a controlled randomized study.
A controlled randomized study was carried out to evaluate the effects of chemotherapy in patients with brain metastases from lung carcinoma. One hundred patients were randomly divided into three… Expand