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Pharmacologic Characterization of the Cloned Human Trace Amine-Associated Receptor1 (TAAR1) and Evidence for Species Differences with the Rat TAAR1
TLDR
The TAAR1 receptor exhibits a pharmacologic profile uniquely different from those of classic monoaminergic receptors, consistent with the structural information that places them in a distinct family of receptors, and suggests the potential for development of TAAR-selective agonists and antagonists to study their physiologic roles.
Treatment of undisplaced femoral neck fractures in the elderly.
TLDR
Osteosynthesis with cannulated screws fixation is a simple, safe, economical, and reasonably effective procedure for the treatment of undisplaced femoral neck fractures in patients older than 80 years.
A population-based study of prevalence and hospital charges in total hip and knee replacement
TLDR
The increasing prevalence of factors affecting hospital charges for primary total hip replacement/total knee replacement (THR/TKR) and use of joint prostheses from different manufacturers can reduce costs without compromising patient satisfaction.
Radiographic and clinical results of posterior dynamic stabilization for the treatment of multisegment degenerative disc disease with a minimum follow-up of 3 years
TLDR
Dynesys is an acceptable alternative to PLIF for the treatment of multisegment lumbar disease and showed a greater improvement in Oswestry Disability Index and visual analogue scale back pain scores at 3 years postoperatively.
Stemness and transdifferentiation of adipose-derived stem cells using L-ascorbic acid 2-phosphate-induced cell sheet formation.
TLDR
A2-P-mediated ASC sheet formation enhanced ASC stemness and transdifferentiation capabilities, thereby representing a promising approach for applications in regenerative medicine.
Comparison of Dynesys posterior stabilization and posterior lumbar interbody fusion for spinal stenosis L4L5.
TLDR
Dynesys posterior stabilization was effective for treating spinal stenosis L4L5 with or without spondylolisthesis, and may be of particular importance for elderly patients, or those with significant comorbidities.
Unreamed interlocking nail versus external fixator for open type III tibia fractures.
TLDR
The results suggest the unreamed interlocking nail is a good choice for the treatment of open type IIIA tibia fractures, but not recommended for the Treatment of opentype IIIB tibia fracture because of the high infection rate.
Impact of Cement Leakage Into Disks on the Development of Adjacent Vertebral Compression Fractures
TLDR
PV is a simple and effective, but not risk-free or complication-free procedure for the treatment of osteoporotic VCF, and patients undergoing PV should be informed of the possibility of new adjacent fractures and the higher risk if cement leaks into the disk.
Reconstruction of ankle and heel defects by a modified wide-base reverse sural flap.
TLDR
It is demonstrated that the design of this modified wide-base reverse sural flap is suitable for flap reconstruction around the ankle and heel; especially for patients who have difficulty in receiving microsurgery.
Reverse LISS plates for unstable proximal femoral fractures.
TLDR
Reverse LISS plate fixation led to complete union of unstable proximal femoral fractures without additional procedures, and this locked-plate device is recommended as the alternative management of instability that is unsuitable for nailing procedures.
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