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In Vitro and In Vivo Activities of a Novel Cephalosporin, BMS-247243, against Methicillin-Resistant and -Susceptible Staphylococci
In conclusion, BMS-247243 has in vitro and in vivo activities against methicillin-resistant staphylococci and thus may prove to be useful in the treatment of infections caused by these multidrug-resistant organisms. Expand
Comparison of a new cephalosporin, BMY 28142, with other broad-spectrum beta-lactam antibiotics
Overall, infections with 18 of 20 strains representing nine genera were responsive to BMY 28142 at doses equivalent to or lower than those of the most effective of the comparison compounds, and the in vitro profile was sustained by the results obtained with experimental infections in mice. Expand
BMY 28100, a new oral cephalosporin
BMY 28100, a new oral cephalosporin with a (Z)-propenyl side chain at the 3 position and a p-hydroxyphenylglycyl substituent at the 7 position, was evaluated in comparison with cefaclor andExpand
Parasites of the German cockroach (Blattella germanica L.) in New York City.
Two nematode and 7 protozoan parasites were found in the first survey of parasites in the German cockroach, Blattella germanica L. Germanica, in New York City, and this is the first report of Hammerschmidtiella diesingi and Endolimax blattae from B. germanicas. Expand
Therapeutic studies of cefepime (BMY 28142) in murine meningitis and pharmacokinetics in neonatal rats
Cefepime was found to be the most active compound against induced meningitis in mice infected with S. pneumoniae and S. agalactiae and in neonatal Rats, where both compounds penetrated well into cerebrospinal fluid and brain tissues of uninfected neonatal rats. Expand
In vitro and in vivo antibacterial activities of BMY 40062, a new fluoronaphthyridone
BMY 40062 was found to be bactericidal, and cross-resistance with other fluoroquinolones was observed, and the efficacy of BMY 40062 reflected its in vitro potency, and exhibited longer half-life, higher maximum concentration in serum, greater area under the curve, and better bioavailability in mice after oral dosing than ciprofloxacin. Expand
Human Isospora belli infection in New York City.
Microbiological evaluation of BB-K 8, a new semisynthetic aminoglycoside.
In experimental infections of mice, BB-K8 was as active as kanamycin in infections caused by kanamycinsensitive bacteria and highly efficacious in infections produced bykanamycin- and/or gentamicin-resistant organisms. Expand