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The 5p15.33 Locus Is Associated with Risk of Lung Adenocarcinoma in Never-Smoking Females in Asia
Genome-wide association studies of lung cancer reported in populations of European background have identified three regions on chromosomes 5p15.33, 6p21.33, and 15q25 that have achieved genome-wideExpand
A Polymorphism in the APE1 Gene Promoter is Associated with Lung Cancer Risk
  • Y. Lo, Y. Jou, +9 authors C. Hsiung
  • Medicine
  • Cancer Epidemiology Biomarkers & Prevention
  • 1 January 2009
Apurinic/apyrimidinic endonuclease 1 (APE1) is an essential enzyme in the base excision repair pathway, which is the primary mechanism for the repair of DNA damage caused by oxidation and alkylation.Expand
Statin use and the risk of cirrhosis development in patients with hepatitis C virus infection.
BACKGROUND & AIMS Several animal studies have shown that statins can inhibit the progression of cirrhosis; however, few clinical studies have been conducted. Previous studies have indicated thatExpand
Prediction of fluid responsiveness in acute respiratory distress syndrome patients ventilated with low tidal volume and high positive end-expiratory pressure*
Objective:Dynamic preload indicators with pulse pressure variation and stroke volume variation are superior to static indicators for predicting fluid responsiveness in mechanically ventilatedExpand
Outcome of lung cancer patients with acute respiratory failure requiring mechanical ventilation.
To assess the weaning outcome of lung cancer patients with acute respiratory failure (ARF) requiring mechanical ventilation, we retrospectively analyzed the database of the respiratory intensive careExpand
The development and psychometric testing of a theory-based instrument to evaluate nurses' perception of clinical reasoning competence.
AIM The purpose of the study was to develop and psychometrically test the Nurses Clinical Reasoning Scale. BACKGROUND Clinical reasoning is an essential skill for providing safe and quality patientExpand
Airway inflammation in smokers and nonsmokers with varying responsiveness to ozone.
Exposure to ozone causes symptoms, changes in lung function, and airway inflammation. We studied whether individuals who differ in lung-function responsiveness to ozone, or in smoking status, alsoExpand
Importin subunit alpha‐2 is identified as a potential biomarker for non‐small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome
The cancer cell secretome may contain potentially useful biomarkers. In this study, we integrated the profiles of secreted proteins in lung cancer cell lines with mRNA expression levels fromExpand
Epidermal Growth Factor Receptor Mutation Status in Stage I Lung Adenocarcinoma with Different Image Patterns
Purpose: Early lung adenocarcinoma may present with ground-glass opacity (GGO) component in computed tomography (CT) scan. Epidermal growth factor receptor (EGFR) mutation had been reported inExpand
Polymerase chain reaction used for the detection of airborne Mycobacterium tuberculosis in health care settings.
BACKGROUND Tuberculosis (TB) has re-emerged as a major infectious disease in several areas in the world. Airborne tubercle bacilli produced by individuals with pulmonary TB and droplet nuclei remainExpand