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Genome-Wide Analysis of Codon Usage and Influencing Factors in Chikungunya Viruses
Chikungunya virus (CHIKV) is an arthropod-borne virus of the family Togaviridae that is transmitted to humans by Aedes spp. mosquitoes. Its genome comprises a 12 kb single-strand positive-sense RNA.… Expand
Evolution of codon usage in Zika virus genomes is host and vector specific
- A. Butt, Izza Nasrullah, R. Qamar, Y. Tong
- Biology, Medicine
- Emerging microbes & infections
- 1 January 2016
The codon usage patterns of viruses reflect the evolutionary changes that allow them to optimize their survival and adapt their fitness to the external environment and, most importantly, their hosts.… Expand
Dynamic Forecasting of Zika Epidemics Using Google Trends
We developed a dynamic forecasting model for Zika virus (ZIKV), based on real-time online search data from Google Trends (GTs) for the dynamic estimation of ZIKV outbreaks. Expand
Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genes and Therapeutic Candidates
Mycobacterium ulcerans, the causative agent of Buruli ulcer, is the third most common mycobacterial disease after tuberculosis and leprosy. The present treatment options are limited and emergence of… Expand
Presence of entomobirnaviruses in Chinese mosquitoes in the absence of Dengue virus co-infection.
Birnaviruses, including the genus Entomobirnavirus, are socio-economically important viruses. Currently, only Drosophila X virus has been formally assigned to the genus Entomobirnavirus, but two more… Expand
Isolation and molecular characterization of a porcine teschovirus 1 isolate from China.
Porcine teschovirus 1 (PTV-1) (Swine/CH/IMH/03) was isolated from piglets in a farm in Inner Mongolia Province, P.R. China. It was confirmed by electron microscopy, RT-PCR, and sequencing. Comparison… Expand
Rapid Assembly of Multiple-Exon cDNA Directly from Genomic DNA
Background Polymerase chain reaction (PCR) is extensively applied in gene cloning. But due to the existence of introns, low copy number of particular genes and high complexity of the eukaryotic… Expand
Removal of Integrated Hepatitis B Virus DNA Using CRISPR-Cas9
- Hao Li, Chunyu Sheng, +20 authors H. Song
- Biology, Medicine
- Front. Cell. Infect. Microbiol.
- 22 March 2017
The presence of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) and the permanent integration of HBV DNA into the host genome confers the risk of viral reactivation and hepatocellular… Expand
Characterization of Enterococcus faecalis Phage IME-EF1 and Its Endolysin
Enterococcus faecalis is increasingly becoming an important nosocomial infection opportunistic pathogen. E. faecalis can easily obtain drug resistance, making it difficult to be controlled in… Expand
Dissemination of IMP-4-encoding pIMP-HZ1-related plasmids among Klebsiella pneumoniae and Pseudomonas aeruginosa in a Chinese teaching hospital
A total of 26 blaIMP-4-carrying strains of Pseudomonas aeruginosa and Klebsiella pneumoniae were isolated from 2009 to 2013 in a Chinese teaching hospital, and these strains can be assigned into… Expand