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Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET
Although no differences were observed in the striatum relative to control subjects, binding of radioligand to D1R was reduced in the prefrontal cortex of schizophrenics, and this reduction was related to the severity of the negative symptoms and to poor performance in the Wisconsin Card Sorting Test.
Age-related changes in human D1 dopamine receptors measured by positron emission tomography
The effects of age on the binding parameters of11C-SCH23390, the highly selective ligand for central D1 dopamine receptors, at specific binding sites in the brain were studied and quantitative estimates of rate constants of association and dissociation were obtained.
Dopamine D1 receptors in Parkinson's disease and striatonigral degeneration: a positron emission tomography study.
The results may explain the different therapeutic responses to levadopa between SND and PD patients, and this technique might prove useful for their differentiation.
D1 dopamine receptor binding in mood disorders measured by positron emission tomography
It is suggested that D1 dopamine receptors in the frontal cortex may be in a different state in patients with bipolar mood disorders.
A detection method of ground glass opacities in chest x-ray CT images using automatic clustering techniques
A new automatic clustering method which is based on a Principal Component (PC) theory, which was examined by many samples (including GGO's shadows) of chest CT images, and proved to be very effective.
Detection of benzodiazepine receptor occupancy in the human brain by positron emission tomography
Benzodiazepine receptor occupancy in the brain following oral administration of clonazepam (CZP) with a dose of 30 μg/kg in six healthy young men and a further dose of 50 μg/kg in one of the subjects
Estimation of the Exposure and a Risk-Benefit Analysis for a CT System Designed for a Lung Cancer Mass Screening Unit
The first report on the benefit-risk analysis for mass screening program of lung cancer in Japan considers that the crossing ages of men and women are rather high when chest radiograph is to be used as a screening test, and recommends that the dose equivalent of lung should be lowered.
Image processing for computer-aided diagnosis of lung cancer by CT(LSCT)
The image processing technique for computer-aided diagnosis of lung cancer by CT(LSCT) is reported, which tries to reduce the image information drastically to be displayed for the doctor, by image processing techniques.