Y. Takahashi

Publications158
h-index31
Citations3,670
Highly Influential Citations40
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A new alkaloid AM-2282 OF Streptomyces origin. Taxonomy, fermentation, isolation and preliminary characterization.
TLDR
The producing strain, AM-2282 was classified as a new species and the name, Streptomyces staurosporeus AWAYA, TAKAHASHI and OMURA, nov. is proposed to show antimicrobial activity against fungi and yeast.
Kitasatosporia, a new genus of the order Actinomycetales.
TLDR
The morphological, cultural, physiological and biochemical characteristics of a new actinomycete strain producing a new antibiotic, setamycin are described and the name Kitasatosporia is proposed, for which the type species is K. setalba.
Tetrahydropyranyl derivatives of daunomycin and adriamycin.
A new antibiotic, cypemycin. Taxonomy, fermentation, isolation and biological characteristics.
A new peptide antibiotic, cypemycin, with a molecular weight of 2,097 (M+H), was isolated from the culture broth of Streptomyces sp. OH-4156. The antibiotic possesses cytocidal activity against P388…
A new antibiotic,, asukamycin, produced by Streptomyces.
TLDR
The empirical formula of antibiotic asukamycin has been proposed as C29H22N2O9 (M.W. 542) and an acute toxicity of the antibiotic in mice is LD50 48.5 mg/kg by intraperitoneal injection and it has no effect on mice when it was administered by 450mg/kg per os.
Triacsins, new inhibitors of acyl-CoA synthetase produced by Streptomyces sp.
Triacsins A and B, new inhibitors of acyl-CoA synthetase, were isolated from the cultured broth of Streptomyces sp. strain SK-1894. The structurally related compounds WS-1228 A and B, known as…
Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. II. Structure determination.
Dephostatin, a novel tyrosine phosphatase inhibitor, was isolated from the culture broth of Streptomyces sp. MJ742-NF5. The structure was elucidated to be 2-(N-methyl-N-nitroso)hydroquinone by…
Studies on subsporin. I. Isolation and characterization of subsporins A, B and C.
Production of deoxyfrenolicin and a new antibiotic, frenolicin B by Streptomyces roseofulvus strain AM-3867.
TLDR
Two antibiotics of frenolicin group were isolated from the fermentation broth of Streptomyces roseofulvus strain No.
Fluostatins A and B, new inhibitors of dipeptidyl peptidase III, produced by Streptomyces sp. TA-3391. I. Taxonomy of producing strain, production, isolation, physico-chemical properties and…
TLDR
Fluostatins A and B were slightly inhibitory against other dipeptidyl peptidases and showed mixed-type (competitive and noncompeptitive) inhibition with human leucine-enkephalin as a substrate.
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