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Interactions of racemic mefloquine and its enantiomers with P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT.
The brain distribution of the enantiomers of the antimalarial drug mefloquine is stereoselective according to the species. This stereoselectivity may be related to species-specific differences in theExpand
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Cerebral uptake of mefloquine enantiomers in fatal cerebral malaria.
PATIENTS AND METHODS The brain disposition of the enantiomers of the antimalarial mefloquine was studied in two post-mortem human cerebral biopsies after oral administration of the racemic mixture.Expand
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Sensitive and rapid method for the simultaneous quantification of five antidepressants with their respective metabolites in plasma using high-performance liquid chromatography with diode-array
A high-performance liquid chromatographic method with diode array detection (HPLC-DAD) has been developed for the simultaneous separation and quantification of imipramine, amitriptyline, maprotiline,Expand
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Stereoselective Passage of Mefloquine Through the Blood‐Brain Barrier in the Rat
The pharmacokinetics of the enantiomers of mefloquine were studied in the rat after administration of a racemic mixture and of the separate enantiomers (+)‐mefloquine and (–)‐mefloquine.
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Monolayer Vanadium‐Doped Tungsten Disulfide: A Room‐Temperature Dilute Magnetic Semiconductor
Abstract Dilute magnetic semiconductors (DMS), achieved through substitutional doping of spin‐polarized transition metals into semiconducting systems, enable experimental modulation of spin dynamicsExpand
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Effects of 25-Hydroxycholesterol on Cholesterol Esterification and Sterol Regulatory Element-binding Protein Processing Are Dissociable
The regulatory pool of cholesterol is located in the endoplasmic reticulum (ER) and is key to how mammalian cells sense and respond to changes in cellular cholesterol levels. The extent ofExpand
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Electron scattering filter design for a single field rotational total skin irradiation
TLDR
The aim of radiotherapy treatment of cutaneous T-cell lymphoma is to irradiate the skin with an appropriately homogeneous dose distribution up to a few millimetres in depth. Expand
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Production of high purity rare earth mixture from iron-rich spent fluid catalytic cracking (FCC) catalyst using acid leaching and two-step solvent extraction process
Acid leaching and a two-step solvent extraction procedure were developed to produce high purity mixture of La and Ce from iron-rich spent FCC catalyst discharged from Dzung Quat refinery (Vietnam).Expand
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Towards efficient extraction of La(III) from spent FCC catalysts by alkaline pre-treatment
Abstract In Vietnam, Dzung Quat Refinery disposes about 7300 tonnes of spent fluid catalytic cracking (SFCC) catalysts per year. The recovery of rare earth metals (La(III), Ce(III),…) contained inExpand
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