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Role of nitric oxide-cGMP pathway in adrenomedullin-induced vasodilation in the rat.
TLDR
Results suggest that the cGMP-specific phosphodiesterase inhibitor E-4021 is involved in the mechanism of AM-induced vasorelaxation, at least in the rat aorta and kidney.
Cadmium metabolism and toxicity in rats after long-term subcutaneous administration.
  • Y. Suzuki
  • Chemistry, Medicine
    Journal of toxicology and environmental health
  • 1 May 1980
TLDR
Male Sprague-Dawley rats were given sc injections of Cd at 0.5 mg/kg body weight, 6 d/wk, for 22 wk and the response of the exposed animals could be divided into three stages, characterized by a steady increase in hepatic and renal Cd and low-level excretion in the urine and a second sharp increase in urinary Cd excretion.
Mechanisms of adrenomedullin-induced vasodilation in the rat kidney.
TLDR
Adrenomedullin-induced renal vasodilation is partially endothelium dependent and is attenuated in deoxycorticosterone acetate-salt hypertension, probably due to endothelial damage.
Effects of vasodilatory beta-adrenoceptor antagonists on endothelium-derived nitric oxide release in rat kidney.
TLDR
The results suggest that several beta-blockers exert their vasodilatory action through the 5-HT1A receptor/NO pathway and that treatment with these beta- blockers may protect against endothelial injury in hypertension.
Cadmium, copper, and zinc excretion and their binding to metallothionein in urine of cadmium exposed rats.
  • Y. Suzuki, H. Yoshikawa
  • Chemistry, Medicine
    Journal of toxicology and environmental health
  • 1 September 1981
TLDR
The results suggest that Metallothionein is directly involved in urinary excretion of Cu in the absence of renal damage and in the excrete of Cd as well as Cu after the appearance of toxicity in Cd-exposed rats.
EFFECTS OF TORASEMIDE ON RENAL HAEMODYNAMICS AND FUNCTION IN ANAESTHETIZED DOGS
TLDR
The effects of torasemide on renal haemodynamics and function employing renal clearance and stop‐flow techniques in anaesthetized dogs and compared these with furosemide are examined.
The normal levels of fluorine in the bone tissue of Japanese subjects.
  • Y. Suzuki
  • Chemistry, Medicine
    The Tohoku journal of experimental medicine
  • 1 December 1979
TLDR
The rib bone and the iliac crest were selected for investigation and the bones of males contained more fluorine than those of females, and the concentration of Ca, P and Mg in bone tissue did not correlate with fluorine concentration.
Differences in the effects of secretin and glucagon on the blood circulation of unanesthetized rats.
TLDR
Carbonized microspheres were injected into the left ventricle of unanesthetized male rats to investigate the changes induced by secretin and glucagon in the distribution of cardiac output to various organs including splanchnic organs.
Sex difference in hypertensive action of metopirone in relation to its plasma levels in the rat.
TLDR
Systolic blood pressure of female rats was elevated to a greater degree and more constantly than that of male rats and there were found at least 3 metabolites of Metopirone in peripheral blood.
Cadmium, copper, and zinc distribution in blood of rats after long-term cadmium administration.
  • Y. Suzuki
  • Chemistry, Medicine
    Journal of toxicology and environmental health
  • 1 February 1981
Cd, Cu, and Zn were determined in plasma and blood cells of rats given daily sc injections of 0.5 mg Cd per kilogram of body weight for 4, 8, and 15 wk. The distribution of these metals in the plasma
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