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Positive Mass Theorem and the Boundary Behaviors of Compact Manifolds with Nonnegative Scalar Curvature
In this paper, we study the boundary behaviors of compact manifolds with nonnegative scalar curvature and with nonempty boundary. Using a general version of Positive Mass Theorem of Schoen-Yau and… Expand
A Novel Cardiolipin-remodeling Pathway Revealed by a Gene Encoding an Endoplasmic Reticulum-associated Acyl-CoA:Lysocardiolipin Acyltransferase (ALCAT1) in Mouse*
- J. Cao, Yanfang Liu, J. Lockwood, P. Burn, Y. Shi
- Medicine, Biology
- Journal of Biological Chemistry
- 23 July 2004
Cardiolipin is a major membrane polyglycerophospholipid that is required for the reconstituted activity of a number of key mitochondrial enzymes involved in energy metabolism. Cardiolipin is… Expand
Beyond triglyceride synthesis: the dynamic functional roles of MGAT and DGAT enzymes in energy metabolism.
Monoacyglycerol acyltransferases (MGATs) and diacylglycerol acyltransferases (DGATs) catalyze two consecutive steps of enzyme reactions in the synthesis of triacylglycerols (TAGs). The metabolic… Expand
Cloning and Functional Characterization of a Mouse Intestinal Acyl-CoA:Monoacylglycerol Acyltransferase, MGAT2*
- J. Cao, J. Lockwood, P. Burn, Y. Shi
- Medicine, Biology
- The Journal of Biological Chemistry
- 18 April 2003
Acyl-CoA:monoacylglycerol transferase (MGAT) plays a predominant role in dietary fat absorption in the small intestine, where it catalyzes the first step of triacylglycerol resynthesis in enterocytes… Expand
Identification and Characterization of a Gene Encoding Human LPGAT1, an Endoplasmic Reticulum-associated Lysophosphatidylglycerol Acyltransferase*[boxs]
Phosphatidylglycerol (PG) is an important membrane polyglycerolphospholipid required for the activity of a variety of enzymes and is a precursor for synthesis of cardiolipin and bis(monoacylglycerol)… Expand
Synapses of Amphids Defective (SAD-A) Kinase Promotes Glucose-stimulated Insulin Secretion through Activation of p21-activated Kinase (PAK1) in Pancreatic β-Cells*
Background: PAK1 is phosphorylated at Thr-423, which is required for glucose-stimulated insulin secretion, but the kinase regulator remains elusive. Results: We identified SAD-A as the kinase that… Expand
Large-sphere and small-sphere limits of the Brown-York mass
In this paper, we will study the limiting behavior of the Brown-York mass of the coordinate spheres in an asymptotically flat manifold. Limiting behaviors of volumes of regions related to coordinate… Expand
Identification and functional characterization of hCLS1, a human cardiolipin synthase localized in mitochondria.
In eukaryotic cells, CLS (cardiolipin synthase) is involved in the final step of cardiolipin synthesis by catalysing the transfer of a phosphatidyl residue from CDP-DAG (diacylglycerol) to PG… Expand
Catalytic properties of MGAT3, a putative triacylgycerol synthases⃞ Published, JLR Papers in Press, December 14, 2006.
Acyl-coenzyme A:monoacylglycerol acyltransferase 3 (MGAT3) is a member of the MGAT family of enzymes that catalyze the synthesis of diacylglycerol (DAG) from monoacylglycerol (MAG), a committed step… Expand
A regulatory role of LPCAT1 in the synthesis of inflammatory lipids, PAF and LPC, in the retina of diabetic mice.
- L. Cheng, X. Han, Y. Shi
- Biology, Medicine
- American journal of physiology. Endocrinology and…
- 1 December 2009
Platelet-activating factor (PAF) and lysophosphatidylcholine (LPC) are potent inflammatory lipids. Elevated levels of PAF and LPC are associated with the onset of diabetic retinopathy and… Expand