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MDMA enhances emotional empathy and prosocial behavior.
3,4-Methylenedioxymethamphetamine (MDMA, 'ecstasy') releases serotonin and norepinephrine. MDMA is reported to produce empathogenic and prosocial feelings. It is unknown whether MDMA in fact altersExpand
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Acute Effects of Lysergic Acid Diethylamide in Healthy Subjects
BACKGROUND After no research in humans for >40 years, there is renewed interest in using lysergic acid diethylamide (LSD) in clinical psychiatric research and practice. There are no modern studies onExpand
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Differential effects of MDMA and methylphenidate on social cognition
Social cognition is important in everyday-life social interactions. The social cognitive effects of 3,4-methylenedioxymethamphetamine (MDMA, ‘ecstasy’) and methylphenidate (both used forExpand
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Pharmacokinetic and pharmacodynamic effects of methylphenidate and MDMA administered alone or in combination.
Methylphenidate and 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') are widely misused psychoactive drugs. Methylphenidate increases brain dopamine and norepinephrine levels by blocking theExpand
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Alterations of consciousness and mystical-type experiences after acute LSD in humans
RationaleLysergic acid diethylamide (LSD) is used recreationally and in clinical research. Acute mystical-type experiences that are acutely induced by hallucinogens are thought to contribute to theirExpand
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Pharmacokinetics and Concentration-Effect Relationship of Oral LSD in Humans
Background: The pharmacokinetics of oral lysergic acid diethylamide are unknown despite its common recreational use and renewed interest in its use in psychiatric research and practice. Methods: WeExpand
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Long-lasting subjective effects of LSD in normal subjects
RationaleLysergic acid diethylamide (LSD) and other serotonergic hallucinogens can induce profound alterations of consciousness and mystical-type experiences, with reportedly long-lasting effects onExpand
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LSD Acutely Impairs Fear Recognition and Enhances Emotional Empathy and Sociality
Lysergic acid diethylamide (LSD) is used recreationally and has been evaluated as an adjunct to psychotherapy to treat anxiety in patients with life-threatening illness. LSD is well-known to induceExpand
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Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans
BACKGROUND AND PURPOSE The use of ±3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) is associated with cardiovascular complications and hyperthermia.
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Direct comparison of the acute subjective, emotional, autonomic, and endocrine effects of MDMA, methylphenidate, and modafinil in healthy subjects
Rationale3,4-Methylenedioxymethamphetamine (MDMA) is used recreationally and investigated as an adjunct to psychotherapy. Methylphenidate and modafinil are psychostimulants that are used to treatExpand
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