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Sepsis in European intensive care units: Results of the SOAP study*
Objective:To better define the incidence of sepsis and the characteristics of critically ill patients in European intensive care units. Design:Cohort, multiple-center, observational study.Expand
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International study of the prevalence and outcomes of infection in intensive care units.
CONTEXT Infection is a major cause of morbidity and mortality in intensive care units (ICUs) worldwide. However, relatively little information is available about the global epidemiology of suchExpand
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Characteristics and outcomes of cancer patients in European ICUs
IntroductionIncreasing numbers of cancer patients are being admitted to the intensive care unit (ICU), either for cancer-related complications or treatment-associated side effects, yet there areExpand
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A positive fluid balance is associated with a worse outcome in patients with acute renal failure
IntroductionDespite significant improvements in intensive care medicine, the prognosis of acute renal failure (ARF) remains poor, with mortality ranging from 40% to 65%. The aim of the presentExpand
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The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects*
Objective:To evaluate the effects of dobutamine on microcirculatory blood flow alterations in patients with septic shock. Design:Prospective, open-label study. Setting:A 31-bed, medico-surgicalExpand
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Microvascular alterations in patients with acute severe heart failure and cardiogenic shock.
BACKGROUND Microvascular blood flow alterations may impair tissue oxygenation and may participate in the development of multiple organ failure in patients with severe heart failure. We hypothesizedExpand
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Diagnosis of ventilator-associated pneumonia: a systematic review of the literature
IntroductionEarly, accurate diagnosis is fundamental in the management of patients with ventilator-associated pneumonia (VAP). The aim of this qualitative review was to compare various criteria ofExpand
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Assessment of the worldwide burden of critical illness: the intensive care over nations (ICON) audit.
BACKGROUND Global epidemiological data regarding outcomes for patients in intensive care units (ICUs) are scarce, but are important in understanding the worldwide burden of critical illness. We,Expand
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Microcirculatory Alterations in Patients With Severe Sepsis: Impact of Time of Assessment and Relationship With Outcome*
Objectives:Sepsis induces microvascular alterations that may play an important role in the development of organ dysfunction. However, the relationship of these alterations to systemic variables andExpand
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Has mortality from acute renal failure decreased? A systematic review of the literature.
PURPOSE To determine mortality rates in patients with acute renal failure during the past decades. METHODS We performed a MEDLINE search using the keywords "acute renal failure" crossed withExpand
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