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Prediction of Recurrence-Free Survival in Postoperative Non–Small Cell Lung Cancer Patients by Using an Integrated Model of Clinical Information and Gene Expression
Purpose: One of the main challenges of lung cancer research is identifying patients at high risk for recurrence after surgical resection. Simple, accurate, and reproducible methods of evaluatingExpand
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Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients.
PURPOSE Lung squamous cell carcinoma (SCC) is the second most prevalent type of lung cancer. Currently, no targeted therapeutics are approved for treatment of this cancer, largely because of a lackExpand
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Functional role of aspartic proteinase cathepsin D in insect metamorphosis
BackgroundMetamorphosis is a complex, highly conserved and strictly regulated development process that involves the programmed cell death of obsolete larval organs. Here we show a novel functionalExpand
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Mycobacterial Characteristics and Treatment Outcomes in Mycobacterium abscessus Lung Disease
Background. Treatment outcomes of patients with Mycobacterium abscessus subspecies abscessus lung disease are poor, and the microbial characteristics associated with treatment outcomes have not beenExpand
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Sixteen Cases of Sclerosing Hemangioma of the Lung Including Unusual Presentations
Sclerosing hemangiomas (SH) of the lung are uncommon tumors and are thought to be benign. However, the biologic behavior of this tumor has not yet been characterized adequately. The clinicopathologicExpand
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Jasmonate-dependent expression of a galactinol synthase gene is involved in priming of systemic fungal resistance in Arabidopsis thaliana
Previously, root colonization by the rhizobacterium, Pseudomonas chlororaphis O6, was shown to induce expression of galactinol synthase conferring systemic resistance against a fungal pathogen inExpand
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Transferrin inhibits stress-induced apoptosis in a beetle.
  • K. Lee, B. Kim, +10 authors B. Jin
  • Biology, Medicine
  • Free radical biology & medicine
  • 1 October 2006
Transferrin in insects is known as an iron transporter, an antibiotic agent, a vitellogenin, and a juvenile hormone-regulated protein. We show here a novel functional role for insect transferrin.Expand
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Lung cancer in never-smoker Asian females is driven by oncogenic mutations, most often involving EGFR
The aim of this study was to determine the distribution of known oncogenic driver mutations in female never-smoker Asian patients with lung adenocarcinoma. We analyzed 214 mutations across 26 lungExpand
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Clinicopathologic Outcomes of Curative Resection for Sarcomatoid Carcinoma of the Lung
Objectives: Sarcomatoid carcinoma of the lung is a very rare and aggressive subtype of non-small cell lung cancer. We explored the clinicopathologic characteristics and surgical outcome of thisExpand
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Discovery of ALK‐PTPN3 gene fusion from human non‐small cell lung carcinoma cell line using next generation RNA sequencing
An increasing number of chromosomal aberrations is being identified in solid tumors providing novel biomarkers for various types of cancer and new insights into the mechanisms of carcinogenesis. WeExpand
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