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- Publications
- Influence
Biotechnological production and applications of coenzyme Q10
- Jin-Ho Choi, Y. Ryu, J. Seo
- Biology, Medicine
- Applied Microbiology and Biotechnology
- 3 March 2005
Coenzyme Q10 is widely used as an essential component of ATP generation in the oxidative phosphorylation process and as an antioxidant preventing lipid peroxidation and scavenging superoxide. It is… Expand
Screening and characterization of a novel esterase from a metagenomic library.
- Y. Kim, Gi-Sub Choi, S. Kim, Gee-Sun Yoon, Y. Kim, Y. Ryu
- Biology, Medicine
- Protein expression and purification
- 1 February 2006
Metagenomes from various environmental soils were screened using alpha-naphthyl acetate and Fast Blue RR for a novel ester-hydrolyzing enzyme on Escherichia coli. Stepwise fragmentations and… Expand
Purification and Characterization of a Novel Erythrose Reductase from Candida magnoliae
- J. Lee, S. Kim, Y. Ryu, J. Seo, Jung-Hoe Kim
- Chemistry, Medicine
- Applied and Environmental Microbiology
- 1 July 2003
ABSTRACT Erythritol biosynthesis is catalyzed by erythrose reductase, which converts erythrose to erythritol. Erythrose reductase, however, has never been characterized in terms of amino acid… Expand
Scale-up of erythritol production by an osmophilic mutant of Candida magnoliae
- Eun-Sung Koh, T. Lee, Do-Yup Lee, H. Kim, Y. Ryu, J. Seo
- Biology, Medicine
- Biotechnology Letters
- 1 December 2003
Erythritol production by an osmophilic mutant of Candida magnoliae was performed in fermentations of up 50 l to develop an optimized commercial process. By simultaneous feeding glucose and yeast… Expand
Batch and fed-batch production of coenzyme Q10 in recombinant Escherichia coli containing the decaprenyl diphosphate synthase gene from Gluconobacter suboxydans
- Y. Park, S. Kim, +5 authors J. Seo
- Biology, Medicine
- Applied Microbiology and Biotechnology
- 1 April 2005
Coenzyme Q10 (CoQ10) is a quinine consisting of ten units of the isoprenoid side-chain. Because it limits the oxidative attack of free radicals to DNA and lipids, CoQ10 has been used as an… Expand
Elevation of glucose 6-phosphate dehydrogenase activity increases xylitol production in recombinant Saccharomyces cerevisiae
- Do-hyun Kwon, Myoung-Dong Kim, Tae-Hee Lee, Yong-Joo Oh, Y. Ryu, J. Seo
- Chemistry
- 1 December 2006
To increase the NAD(P)H-dependent xylitol production in recombinant Saccharomyces cerevisiae harboring the xylose reductase gene from Pichia stipitis, the activity of glucose 6-phosphate… Expand
Molecular cloning and biochemical characterization of a novel erythrose reductase from Candida magnoliae JH110
BackgroundErythrose reductase (ER) catalyzes the final step of erythritol production, which is reducing erythrose to erythritol using NAD(P)H as a cofactor. ER has gained interest because of its… Expand
Homomeric and heteromeric interactions of the extracellular domains of death receptors and death decoy receptors.
- Hyun-Wook Lee, S. Lee, H. Lee, Y. Ryu, M. Kwon, Y. Kim
- Biology, Medicine
- Biochemical and biophysical research…
- 20 May 2005
Death receptors (DRs) can induce apoptosis by oligomerization with TRAIL, whereas death decoy receptors (DcRs) cannot, due to their lack of functional intracellular death domains. However, it is not… Expand
Amplification of 1-deoxy-d-xyluose 5-phosphate (DXP) synthase level increases coenzyme Q10 production in recombinant Escherichia coli
- S. Kim, Myoung-Dong Kim, Jin-Ho Choi, S. Kim, Y. Ryu, J. Seo
- Biology, Medicine
- Applied Microbiology and Biotechnology
- 11 March 2006
For the enhancement of coenzyme Q10 (CoQ10) production, 1-deoxy-d-xylulose 5-phosphate (DXP) synthase of Pseudomonas aeruginosa was constitutively coexpressed in a recombinant Escherichia coli… Expand
Screening, production and properties of a stereospecific esterase from Pseudomonas sp. S34 with high selectivity to (S)-ketoprofen ethyl ester
- Geun-Joong Kim, Gi-Sub Choi, Ji-youn Kim, J. Lee, D. Jo, Y. Ryu
- Chemistry
- 7 March 2002
Abstract To isolate novel strains expressing an esterase that hydrolyzed the rac -ketoprofen ethyl ester to ( S )-ketoprofen in the stereospecific manner, we screened broad ecological niches and soil… Expand