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Activity of the Inflammatory Process in Different Types of Unstable Atherosclerotic Plaques
Inflammatory biomarkers and chemoattractants characteristic and important for different types (lipid; inflammatory erosive; degenerative necrotic) of unstable plaques in coronary arteries were
Oxidation and Endothelial Dysfunction Biomarkers of Atherosclerotic Plaque Instability. Studies of the Vascular Wall and Blood
TLDR
Of these blood biomarkers, only NO metabolites, oxidized proteins, and sVCAM correlated with the presence of unstable atherosclerotic plaques, and a significant correlation between the levels of biomarkers in the vascular wall and blood was detected only for LPO parameters.
Balance of Fatty Acids and Their Correlations with Parameters of Lipid Metabolism and Markers of Inflammation in Men with Coronary Atherosclerosis
TLDR
Lipid metabolism disturbances in coronary atherosclerosis were accompanied by changes in not only lipid spectrum and inflammation markers, but also fatty acids balance, revealing multiple correlations between the studied fatty acids.
Antioxidant and endothelium-stabilizing effects of simvaglyzin on rabbits with experimental hypercholesterolemia
Simvaglyzin, a complex compound of simvastatin and glycyrrhizic acid, administered to rabbits with experimental hypercholesterolemiain in doses equivalent to 66.6 and 40 µg/kg simvastatin exhibited
Blood Level of Osteonectin in Stenosing Atherosclerosis and Calcinosis of Coronary Arteries
TLDR
The results indicate that osteonectin as a marker of stromal stem cells with osteogenic potential presumably plays an important role in atherogenesis and can serve as a new biomarker of stenosing atherosclerosis and calcinosis of coronary arteries.
ANALYSIS OF DIFFERENTIAL ExPRESSION OF MATRIx METALLOPROTEASES IN STABLE AND UNSTABLE ATHEROSCLEROTIC LESIONS BY A METHOD OF FULL GENOME SEQUENCING OF RNA: PILOT STUDY
TLDR
With the IEA it was found that fatty streaks and young stable atheromas of coronary arteries have an increased concentration of MMP-3 and decreased activity of tissue inhibitor of metalloproteases and there were significant differences obtained, of expression levels in stable atherosclerotic fibrous plaque and unstable plaque of dystrophic-necrotic type.
Study of cholesterol-lowering effect and safety of simvaglisin on rabbit model of hypercholesterolemia
Using rabbit model of experimental hypercholesterolemia we showed that the hypocholesterolemic effect of simvaglisin, a complex preparation containing simvastatin and glycyrrhizic acid, in doses
Effects of Simvaglyzin and Atorvaglyzin on the Expression of 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase in Rat Liver
Activity and levels of protein and mRNA of 3-hydroxy-3-methyl-glutaryl-CoA reductase were estimated in rat liver after the administration of atorvastatin and simvastatin and their complexes with
Associations of Osteocalcin, Osteoprotegerin, and Calcitonin with Inflammation Biomarkers in Atherosclerotic Plaques of Coronary Arteries
TLDR
The results suggest that severe vascular calcification can be regarded as non-specific marker of atherosclerotic plaques and Instability of Atherosclerosis is associated with higher level of calcification.
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