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Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis
TLDR
A new susceptibility locus on chromosome 6q24.1 in Japanese is identified and the most significantly associated SNP, rs6570507, was in GPR126 (encoding G protein–coupled receptor 126), which was replicated in Han Chinese and European-ancestry populations.
Melatonin Receptor 1B (MTNR1B) Gene Polymorphism Is Associated With the Occurrence of Adolescent Idiopathic Scoliosis
TLDR
Polymorphisms of the promoter of MTNR1B gene were associated with AIS, but not with the curve severity in AIS patients, which suggested that MT NR1B was an AIS predisposition gene.
Top Theories for the Etiopathogenesis of Adolescent Idiopathic Scoliosis
TLDR
An overview of the current main hypothetical “concepts” on the etiopathogenesis of AIS is provided to stimulate further innovative thoughts, research, and especially collaborative research in this area of great interest.
Promoter polymorphism of matrilin-1 gene predisposes to adolescent idiopathic scoliosis in a Chinese population
TLDR
It is concluded that the tagSNP rs1149048 polymorphism in the MATN1 promoter region was associated with both susceptibility and disease progression in AIS.
Metal artifacts reduction using monochromatic images from spectral CT: evaluation of pedicle screws in patients with scoliosis.
  • Yang Wang, B. Qian, +5 authors B. Zhu
  • Medicine
    European journal of radiology
  • 1 August 2013
TLDR
Compared to conventional polychromatic images, monochromatic images acquired from dual-energy CT provided superior image quality with much reduced metal artifacts of pedicle screws in patients with scoliosis.
Discrepancy between radiographic shoulder balance and cosmetic shoulder balance in adolescent idiopathic scoliosis patients with double thoracic curve
TLDR
The results indicated that radiographic parameters could only partially reflect the shoulder cosmetic appearances, and spine surgeons should pay more attention to the cosmetic shoulder balance rather than radiographic shoulder balance.
Decreased Circulating Leptin Level and Its Association With Body and Bone Mass in Girls With Adolescent Idiopathic Scoliosis
TLDR
An abnormal growth pattern, a marked decrease of circulating leptin, and a association between leptin and body weight, BMI, other growth parameters, and BMC/BMD suggest that leptin might play an important role in the lower body and bone mass in AIS girls.
Pedicle subtraction osteotomy through pseudarthrosis to correct thoracolumbar kyphotic deformity in advanced ankylosing spondylitis
TLDR
PSO can be safely performed through the site of pseudarthrotic lesion in AS patients with pseudarthrosis and kyphotic deformity and three patients with neurological deficits had complete recovery of neurological function.
Association of Estrogen Receptor Gene Polymorphisms With Susceptibility to Adolescent Idiopathic Scoliosis
TLDR
The XbaI site polymorphism of estrogen receptor gene may be associated with a risk of AIS, and this study included 202 patients with AIS and 174 healthy controls.
Optimal surgical care for adolescent idiopathic scoliosis: an international consensus
TLDR
International consensus was found on many aspects of what does and does not constitute optimal operative care for adolescents with AIS, which will aid health care providers worldwide define appropriate care in their regions.
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