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Prognostic value of microsatellite instability in resectable pancreatic cancer.
The significance of microsatellite instability (MSI) as a prognostic predictor for resectable pancreatic cancer patients was examined. Forty-six histologically confirmed pancreatic cancer patientsExpand
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In Vitro Migratory potential of rat quiescent hepatic stellate cells and its augmentation by cell activation
In liver injury, hepatic stellate cells are considered to depart from the sinusoidal wall and accumulate in the necrotic lesion through migration and proliferation. In this study, we investigated theExpand
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Expression of cellular prion protein in activated hepatic stellate cells.
Suppression subtractive hybridization was used to clone genes associated with the activation of hepatic stellate cells and 13 genes were found to be dominantly expressed in activated stellate cells.Expand
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TNP-470 blockage of VEGF synthesis is dependent on MAPK/COX-2 signaling pathway in PDGF-BB-activated hepatic stellate cells.
Angiogenesis is a key pathogenic event in hepatic fibrogenesis, which is mediated by activated hepatic stellate cells (HSCs). TNP-470 is a known anti-angiogenic agent in cancer, and in this study, weExpand
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CD44v6 may influence ovarian cancer cell invasion and migration by regulating the NF-κB pathway
Ovarian cancer (OC) has the worst prognosis among all malignancy types in females worldwide according to epidemiological studies in 2017. Although radiotherapy, chemotherapy and surgical treatmentExpand
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Suitability of a new stable acetal analogue of aldoifosphamide for purging leukemic cells from human bone marrow.
The in vitro cytotoxic properties of acetaldoifosphamide, a new chemically stable bis-acetate analogue of aldoifosphamide that requires enzymatic activation by cellular carboxylate esterases, hasExpand
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An improved procedure for the synthesis of 4-methylimidazol-2-one
Abstract A novel one-pot synthetic method of 4-methylimidazol-2-one is described. The target compound is conveniently synthesized from sodium diformylamide, a modified Gabriel reagent prepared,Expand