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Arthroscopic treatment of popliteal cysts: clinical and magnetic resonance imaging results.
- J. H. Ahn, S. Lee, J. Yoo, M. J. Chang, Y. Park
- Arthroscopy : the journal of arthroscopic…
- 1 October 2010
PURPOSE This study examined the functional and magnetic resonance imaging (MRI) outcomes of popliteal cysts with combined intra-articular pathologies that were treated arthroscopically by… Expand
RNA aptamer-conjugated liposome as an efficient anticancer drug delivery vehicle targeting cancer cells in vivo.
- Si Eun Baek, K. Lee, +4 authors D. Kim
- Chemistry, Medicine
- Journal of controlled release : official journal…
- 28 December 2014
To minimize the systemic toxicity prevalent to chemotherapeutics, we designed a novel anticancer drug-encapsulating liposome conjugated with an RNA aptamer specific to the prostate specific membrane… Expand
In vitro and in vivo gene-transferring characteristics of novel cationic lipids, DMKD (O,O'-dimyristyl-N-lysyl aspartate) and DMKE (O,O'-dimyristyl-N-lysyl glutamate).
Abstract We chemically synthesized two different cationic lipids consisting of a core of lysine, two C-14 hydrocarbon chains, and either aspartatic acid or glutamic acid. The lipids were assigned the… Expand
Hepatic control elements promote long‐term expression of human coagulation factor IX gene in hydrodynamically transfected mice
- H. S. Kim, J. C. Kim, Y. Lee, J. Kim, Y. Park
- Biology, Medicine
- The journal of gene medicine
- 1 July 2011
Long‐term expression of the delivered target gene is critical for successful gene therapy. Recently, hepatic control region I (HCR I) originating from the apolipoprotein (apo)C‐I pseudogene was shown… Expand
Inhibitory effect of the salmosin gene transferred by cationic liposomes on the progression of B16BL6 tumors.
Salmosin is a novel disintegrin containing the Arg-Gly-Asp sequence that significantly inhibits platelet aggregation, basic fibroblast growth factor-induced endothelial cell proliferation, and tumor… Expand
Tumor-Directed Targeting of Liposomes
- Y. Park
- Bioscience reports
- 1 April 2002
Tumor-specific targeting is a critical goal in the research area of liposomal drug delivery. Identification of the specific interactions between ligands and target tumor cells is a principle… Expand
Cancer-targeted Nucleic Acid Delivery and Quantum Dot Imaging Using EGF Receptor Aptamer-conjugated Lipid Nanoparticles
Co-application of fluorescent quantum dot nanocrystals and therapeutics has recently become a promising theranostic methodology for cancer treatment. We developed a tumor-targeted lipid nanocarrier… Expand
Inhibition of angiogenesis and tumor progression by hydrodynamic cotransfection of angiostatin K1-3, endostatin, and saxatilin genes
In vivo expression of angiostatin and endostatin, two different types of endothelial cell growth inhibitor, have been reported to inhibit vascularization in tumor tissues, resulting in tumor growth… Expand
Immuno-PET Imaging and Radioimmunotherapy of 64Cu-/177Lu-Labeled Anti-EGFR Antibody in Esophageal Squamous Cell Carcinoma Model
- I. Song, T. S. Lee, +9 authors S. M. Lim
- Medicine, Chemistry
- The Journal of Nuclear Medicine
- 25 February 2016
Immuno-PET provides valuable information about tumor location, phenotype, susceptibility to therapy, and treatment response, especially to targeted radioimmunotherapy. In this study, we prepared… Expand
Leukemia-specific siRNA delivery by immunonanoplexes consisting of anti-JL1 minibody conjugated to oligo-9 Arg-peptides
Targeted mRNA degradation by short interfering RNAs (siRNAs) offers a great potential to treat cancers. siRNA therapeutics for leukemias are, however, hindered by poor intracellular uptake, limited… Expand