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Fatty acid composition, physicochemical properties, antioxidant and cytotoxic activity of apple seed oil obtained from apple pomace.
- M. Walia, K. Rawat, S. Bhushan, Y. Padwad, Bikram Singh
- Chemistry, MedicineJournal of the science of food and agriculture
- 30 March 2014
The physicochemical properties of apple seed oil were comparable with edible food oil, indicating its better stability and broad application in the food and pharmaceutical industries, and its potential as an anticancer agent.
HIF-1 in cancer therapy: two decade long story of a transcription factor
New evidences indicate role of many HIF-induced proteomic and genomic alterations in malignant progression by mediating a myriad of genes stimulating angiogenesis, anaerobic metabolism and survival of cancer cells in O2-deficient microenvironment.
Validation of ethnomedicinal potential of Tinospora cordifolia for anticancer and immunomodulatory activities and quantification of bioactive molecules by HPTLC.
Effect of Hippophae rhamnoides leaf extract against Dengue virus infection in human blood-derived macrophages.
Epigallocatechin gallate suppresses premature senescence of preadipocytes by inhibition of PI3K/Akt/mTOR pathway and induces senescent cell death by regulation of Bax/Bcl-2 pathway
- Ravi Kumar, Anamika Sharma, A. Kumari, A. Gulati, Y. Padwad, Rohit Sharma
- 19 November 2018
Results collectively show that EGCG acts as an mTOR inhibitor, SASP modulator as well as a potential senolytic agent thereby indicating its multi-faceted attributes that could be useful for developing anti-aging or age-delaying therapies.
Chemical Composition and In Vitro Cytotoxicity of Essential Oils from Leaves and Flowers of Callistemon citrinus from Western Himalayas
Higher concentration of 1,8-cineole and/or synergistic effect of the overall composition were probably responsible for the efficacy of flower and leaf oils against the tested cells.
Anti-inflammatory activity of Seabuckthorn (Hippophae rhamnoides) leaves.
Phenolic constituents from apple tree leaves and their in vitro biological activity
MAPKAPK2: the master regulator of RNA-binding proteins modulates transcript stability and tumor progression
The importance of MK 2 as the master regulator of RBPs and its role in the regulation of transcript stability, tumor progression, as well as the possibility of use of MK2 as a therapeutic target in tumor management are highlighted.
Dengue virus infection activates cellular chaperone Hsp70 in THP-1 cells: downregulation of Hsp70 by siRNA revealed decreased viral replication.
- Y. Padwad, K. P. Mishra, Monika Jain, S. Chanda, L. Ganju
- Biology, MedicineViral immunology
- 8 December 2010
Evidence is provided that an increased level of Hsp70 expression in dengue-virus-infected THP-1 cells assists in viral replication by escaping the antiviral effect of type 1 interferon.