• Publications
  • Influence
Isolation and structure of prorocentrolide B, a fast-acting toxin from Prorocentrum maculosum.
A new toxin, prorocentrolide B (1), has been isolated following bioassay-guided fractionation of a BuOH extract of the tropical dinoflagellate, Prorocentrum maculosum Faust. This compound produces aExpand
  • 72
  • 4
Exploring the structural basis of neurotoxicity in C(17)-polyacetylenes isolated from water hemlock.
Water hemlock, Cicuta virosa, belonging to the Umbelliferae, is well-known as a toxic plant responsible for lethal poisonings in humans as well as animals, causing tonic and clonic convulsions andExpand
  • 55
  • 4
Some chemical properties of maitotoxin, a putative calcium channel agonist isolated from a marine dinoflagellate.
Maitotoxion, a putative Ca2+ channel agonist, was isolated from cultures of the marine dinoflagellate Gambierdiscus toxicus as a colorless amorphous solid. The toxin reacted positively toExpand
  • 115
  • 2
Antihepatotoxic principles of Curcuma longa rhizomes.
An extract of the crude drug “ukon”, the rhizomes of CURCUMA LONGA, exhibited intense preventive activity against carbon tetrachloride-induced liver injury IN VIVO and IN VITRO. The extract wasExpand
  • 221
  • 2
Hypotensive principles of Uncaria hooks.
A methanol extract of the Oriental crude drug “chōtōkō”, UNCARIA hooks, elicited a strong and long-lasting hypotension on injection into rats. The activity differed considerably from the effectsExpand
  • 42
  • 2
Neolignans and Lignans of Nardostachys jatamansi Roots1.
  • 66
  • 2
A monogalactosyl diacylglycerol from a cultured marine dinoflagellate, Scrippsiella trochoidea.
A novel monogalactosyl diacylglycerol [1] has been isolated from a cultured marine dinoflagellate Scrippsiella trochoidea, and its structure was elucidated by spectroscopic methods
  • 32
  • 2
Analgesic and antihepatotoxic actions of dianosides, triterpenoid saponins of Dianthus superbus var. longicalycinus herbs.
The triterpenoid saponins isolated from the herbs of DIANTHUS SUPERBUS var. LONGICALYCINUS have been evaluated for analgesic and antihepatotoxic activities. The saponins of the gypsogenic acid seriesExpand
  • 26
  • 2
Studies on zoapatle, II. Leucanthanolide, a novel sesquiterpene lactone from Montanoa leucantha ssp. leucantha.
A sesquiterpene lactone given the trivial name leucanthanolide, from the Mexican zoapatle plant (Montanoa leucantha), long used as an herbal remedy, was isolated and was found to have cytotoxicityExpand
  • 10
  • 2
Phrymarolin-I, a Novel Lignan from Phryma leptostachya L.
A novel lignan, named phrymarolin-I, has been isolated from Phryma leptostachya L. The structure (I) for phrymarolin-I represents the first example of a lignan characterized by aExpand
  • 15
  • 2