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Prediction of immediate and future rewards differentially recruits cortico-basal ganglia loops
- Saori C. Tanaka, K. Doya, G. Okada, K. Ueda, Y. Okamoto, S. Yamawaki
- Psychology, BiologyNature Neuroscience
- 1 August 2004
Brain mechanisms for reward prediction at different time scales in a Markov decision task and graded maps of time scale within the insula and the striatum suggest differential involvement of the cortico-basal ganglia loops in reward prediction in different time scale.
Serotonin Differentially Regulates Short- and Long-Term Prediction of Rewards in the Ventral and Dorsal Striatum
The results suggest that serotonin controls the time scale of reward prediction by differentially regulating activities within the striatum.
Does low self-esteem enhance social pain? The relationship between trait self-esteem and anterior cingulate cortex activation induced by ostracism.
Functional magnetic resonance imaging was used to experimentally investigate whether trait self-esteem would be related to social pain responsiveness, and revealed a positive connectivity between the dorsal anterior cingulate and prefrontal cortices for the lower traitSelf-esteem group, and a corresponding negative connectivity for the higher trait Selfesteem group.
Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain
- Takuji Fukumoto, S. Morinobu, Y. Okamoto, A. Kagaya, S. Yamawaki
- Biology, PsychologyPsychopharmacology
- 1 October 2001
The results suggest that the chronic administration of mood stabilizers may produce a neurotrophic effect mediated by the upregulation of BDNF in the rat brain.
DNA Methylation Profiles of the Brain-Derived Neurotrophic Factor (BDNF) Gene as a Potent Diagnostic Biomarker in Major Depression
Results indicate that classification based on the DNA methylation profiles of CpG I of the BDNF gene may be a valuable diagnostic biomarker for major depression.
Self-referential processing of negative stimuli within the ventral anterior cingulate gyrus and right amygdala
Decreased ventral anterior cingulate cortex activity is associated with reduced social pain during emotional support
- K. Onoda, Y. Okamoto, Ken'ichiro Nakashima, H. Nittono, M. Ura, S. Yamawaki
- PsychologySocial neuroscience
- 8 September 2009
The results suggest that the ventral ACC underlies social pain, and that emotional support enhances prefrontal cortex activity, which in turn may lead to a weakened affective response.
Brain activity during expectancy of emotional stimuli: an fMRI study
- K. Ueda, Y. Okamoto, G. Okada, H. Yamashita, T. Hori, S. Yamawaki
- Biology, PsychologyNeuroreport
- 20 January 2003
The findings suggest that the amygdala and anterior cingulate cortex may play an important role in the expectancy of unpleasant stimuli and that the input of this negative information is modulated by these specific brain areas.
Negative correlation between right prefrontal activity during response inhibition and impulsiveness: A fMRI study
- Sh. Asahi, Y. Okamoto, G. Okada, S. Yamawaki, N. Yokota
- Psychology, BiologyEuropean Archives of Psychiatry and Clinical…
- 1 August 2004
The results suggest that the RDLPFC is the area most sensitive to differences in individual motor impulsiveness and its activity may be an indicator of the individual capacity for response inhibition.
A small number of abnormal brain connections predicts adult autism spectrum disorder
A novel machine-learning algorithm is developed that identifies a small number of FCs that separates ASD versus TD and leaves open the viable possibility of exploring neuroimaging-based dimensions quantifying the multiple-disorder spectrum.