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Antioxidant, gallic acid, induces apoptosis in HL-60RG cells.
Gallic acid, a naturally occurring plant phenol with antioxidative activity, was found to induce cell death in promyelocytic leukemia HL-60RG cells, although many antioxidants are well known toExpand
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Anti-inflammatory testing methods: comparative evaluation of mice and rats.
The possibility of using mice in place of rats on the anti-inflammatory screening tests was investigated. The diversities of the responses between mice and rats on screening tests, that is,Expand
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Structural transformation of saikosaponins by gastric juice and intestinal flora.
Structural transformation of saikosaponin a and saikosaponin d, main components of Bupleuri Radix, were investigated using rat gastric juice (pH 1.5) and mouse intestinal flora in vitro and theExpand
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Role of reactive oxygen species in gallic acid-induced apoptosis.
We earlier demonstrated that gallic acid (3,4,5-trihydroxybenzoic acid) induced apoptosis in promyelocytic leukemia HL-60RG cells, which was inhibited by catalase and intracellular Ca2+ chelator. InExpand
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Selective induction of cell death in cancer cells by gallic acid.
Gallic acid (3,4,5-trihydroxybenzoic acid) is a naturally occurring plant phenol obtained by the hydrolysis of tannins and is know to show some pharmacological activities. In screening anti-cancerExpand
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Differential Interactions of the C terminus and the Cytoplasmic I-II Loop of Neuronal Ca2+ Channels with G-protein α and βγ Subunits
The present study was designed to obtain evidence for direct interactions of G-protein α (Gα) and βγ subunits (Gβγ) with N- (α1B) and P/Q-type (α1A) Ca2+ channels, using synthetic peptides and fusionExpand
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Effect of shosaikoto, a Japanese and Chinese traditional herbal medicinal mixture, on the mitogenic activity of lipopolysaccharide: a new pharmacological testing method.
Two in vitro experimental systems were compared to evaluate the pharmacological effects of Shosaikoto, a Japanese and Chinese traditional herbal medicinal mixture, on the mitogenic activity ofExpand
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Iridoid glucosides from Veronica hederifolia.
A new iridoid glucoside, urphoside A, and six known iridoid glucosides, pikuroside, aucubin, veronicoside, catalposide, amphicoside, and verminoside, were isolated from Veronica hederifolia togetherExpand
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Comparative studies of the stereoisomers of glycyrrhetinic acid on anti-inflammatory activities.
Anti-inflammatory activity of the stereoisomers, 18 alpha and 18 beta-glycyrrhetinic acid (18 alpha and 18 beta-GA), obtained from Glycyrrhizae Radix, was investigated by using carrageenan-inducedExpand
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Studies on the combination of Glycyrrhizae Radix in Shakuyakukanzo-To.
The pharmacological properties of the five samples of glycyrrhizic acid, paeoniflorin, the extracts of Glycyrrhizae Radix, the extracts of Paeoniae Radix and a preparation of Chinese drugExpand
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