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Histone acetyltransferase activity in rat hepatomas
- H. Grunicke, Yasukazu Yamada, Y. Natsumeda, W. Helliger, B. Puschendorf, G. Weber
- Biology, MedicineJournal of Cancer Research and Clinical Oncology
The behaviour of histone acetyltransferase activity was elucidated in normal rat liver and in a spectrum of well-characterized rat hepatomas of slow, intermediate and rapid growth rates, and the acetyl transferase specific activity was higher than in the corresponding normal livers and the rise correlated positively with the proliferation rates of the tumors.