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Excess Lymphangiogenesis Cooperatively Induced by Macrophages and CD4(+) T Cells Drives the Pathogenesis of Lymphedema.
- F. Ogata, K. Fujiu, +7 authors I. Manabe
- The Journal of investigative dermatology
- 1 March 2016
Lymphedema is a debilitating progressive condition that severely restricts quality of life and is frequently observed after cancer surgery. The mechanism underlying lymphedema development remains… Expand
A heart–brain–kidney network controls adaptation to cardiac stress through tissue macrophage activation
Heart failure is a complex clinical syndrome characterized by insufficient cardiac function. In addition to abnormalities intrinsic to the heart, dysfunction of other organs and dysregulation of… Expand
A case of transient 2:1 atrioventricular block, resolved by thyroxine supplementation for subclinical hypothyroidism.
A 42-year-old man was admitted to our hospital with palpitation attacks. Holter ECG showed 2:1 atrioventricular block and bradycardia with the minimum heart rate of 44 beats/min. There was a possible… Expand
The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages
Proinflammatory cytokine production in macrophages involves multiple regulatory mechanisms, which are affected by environmental and intrinsic stress. In particular, accumulating evidence has… Expand
A case of early phase dialysis associated effusive constrictive pericarditis with distinct surgical findings.
- Y. Nakayama, Yoshitaka Ohtani, N. Kobayakawa, J. Kobayashi, Y. Kaneko, T. Aoyagi
- International heart journal
- 1 September 2009
A 55-year-old male patient with a 10 year history of hemodialysis was admitted for examination of pericardial effusion. Specific echocardiography, MRI, and cardiac catheterization findings strongly… Expand
iBTA-induced bovine Biosheet for repair of abdominal wall defects in a beagle model: proof of concept
IntroductionWe evaluated the usefulness of xeno-Biosheets, an in-body tissue architecture-induced bovine collagenous sheet, as repair materials for abdominal wall defects in a beagle model.Materials… Expand
Can Anti-inflammatory Therapy Prevent Atrial Fibrillation in Myocardial Infarction Patients?
: An error appeared in the article titled "Can Anti-inflammatory Therapy Prevent Atrial Fibrillation in Myocardial Infarction Patients?" by Yukiteru Nakayama and Katsuhito Fujiu (Vol. 59, No. 1, 3-5,… Expand
Maladaptive Alterations of Autonomic Nerve System in Cardiovascular Disorders.
Sudden unexpected nocturnal death syndrome (SUNDS) occurs predominantly in Southeast Asia, and the young healthy victims are struck by unexplained deaths during nocturnal sleep. The predilection time… Expand
Przypadek przejściowego bloku przedsionkowo-komorowego z przewodzeniem 2:1, który ustąpił po suplementacji tyroksyną zastosowaną w celu leczenia subklinicznej postaci niedoczynności tarczycy
Mezczyzne w wieku 42 lat przyjeto do szpitala, w ktorym pracują autorzy niniejszego doniesienia, z powodu napadow kolatania serca. W holterowskim badaniu EKG wykazano blok przedsionkowo-komorowy (AV)… Expand
A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation
- Y. Nakayama, K. Fujiu, +14 authors Ichiro Manabe
- Medicine, Chemistry
- Proceedings of the National Academy of Sciences
- 8 June 2020
Significance Proper resolution of inflammation is essential for restoration of homeostasis. Macrophages are particularly important for this process and dynamically change their functional phenotypes… Expand