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Morphometric and cytogenetic characteristics of testicular germ cells and Sertoli cell secretory function in men with non-mosaic Klinefelter's syndrome.
- Y. Yamamoto, N. Sofikitis, Y. Mio, D. Loutradis, A. Kaponis, I. Miyagawa
- Medicine, Biology
- Human reproduction
- 1 April 2002
BACKGROUND Klinefelter's syndrome is the most frequent chromosomal abnormality in infertile men. In this study, the chromosomes of round spermatids and spermatogonia/primary spermatocytes from men… Expand
Age as a limiting factor for successful sperm retrieval in patients with nonmosaic Klinefelter's syndrome.
OBJECTIVE To determine factors affecting successful sperm retrieval by testicular sperm extraction in patients with nonmosaic Klinefelter's syndrome. DESIGN Medical record analysis for nonmosaic… Expand
Reduced implantation rate associated with a subtle rise in serum progesterone concentration during the follicular phase of cycles stimulated with a combination of a gonadotrophin-releasing hormone…
Our objective was to assess the effects of subtle increases in serum progesterone concentration (1.0-2.0 ng/ml) on the outcome of in-vitro fertilization (IVF), particularly on the quality of embryos,… Expand
Time-lapse cinematography of dynamic changes occurring during in vitro development of human embryos.
OBJECTIVE The purpose of this study was to clarify developmental changes of early human embryos by using time-lapse cinematography (TLC). STUDY DESIGN For human ova, fertilization and cleavage,… Expand
Efforts to create an artificial testis: culture systems of male germ cells under biochemical conditions resembling the seminiferous tubular biochemical environment.
- N. Sofikitis, Eric Pappas, +12 authors I. Miyagawa
- Biology, Medicine
- Human reproduction update
- 1 May 2005
Induction of meiotic and post-meiotic alterations of male germ cells in vitro has been the target of several research efforts since 1960. However, to date, the establishment of an ideal culture… Expand
Subtle rise in serum progesterone during the follicular phase as a predictor of the outcome of in vitro fertilization.
- Y. Mio, A. Sekijima, T. Iwabe, Y. Onohara, T. Harada, N. Terakawa
- Fertility and sterility
- 1 July 1992
OBJECTIVE To investigate the effects of subtle rises in serum progesterone (P) during the follicular phase on the outcome of in vitro fertilization and embryo transfer (IVF-ET). DESIGN, PATIENTS… Expand
Ooplasmic injection of elongating spermatids for the treatment of non-obstructive azoospermia.
We applied the technique of ooplasmic elongating spermatid injection to the treatment of non-obstructive azoospermia. Mature oocytes were injected with elongating spermatids isolated from testicular… Expand
Altering the timing of human chorionic gonadotropin injection according to serum progesterone (P) concentrations improves embryo quality in cycles with subtle P rise.
- T. Harada, C. Katagiri, N. Takao, T. Toda, Y. Mio, N. Terakawa
- Fertility and sterility
- 1 March 1996
OBJECTIVE To investigate the effect of earlier administration of hCG according to serum concentrations of P on the outcome of IVF-ET in cycles in which a subtle rise in serum P (1.0 to 2.0 ng/mL;… Expand
Highly sensitive quantitative telomerase assay of diagnostic testicular biopsy material predicts the presence of haploid spermatogenic cells in therapeutic testicular biopsy in men with Sertoli…
The role of a telomerase assay in the recognition of Sertoli cell-only syndrome with testicular foci of haploid cells was evaluated. Men with Sertoli cell-only syndrome (n = 23) were given a new… Expand
Isoflurane protects cardiomyocytes and mitochondria by immediate and cytosol‐independent action at reperfusion
- D. Pravdic, Y. Mio, +4 authors M. Bienengraeber
- Medicine, Chemistry
- British journal of pharmacology
- 1 May 2010
Background and purpose: The volatile anaesthetic isoflurane protects the heart from ischaemia and reperfusion (I/R) injury when applied at the onset of reperfusion [anaesthetic postconditioning… Expand