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Stellettin A, a new triterpenoid pigment from the marine sponge Stelletta tenuis.
A new isomalabaricane triterpenoid, stellettin A, was isolated from the sponge Stelletta tenuis collected off Hainan Island, People's Republic of China by analysis of its spectral data and reference to related compounds. Expand
Antineoplastic agents. 522. Hernandia peltata (Malaysia) and Hernandia nymphaeifolia (Republic of Maldives).
Evaluation against the murine P388 lymphocytic leukemia cell line and human tumor cell lines showed podophyllotoxin derivatives 2 and 3 to be strong cancer cell line growth inhibitors and substances 4, 5, 8, and 15 to have marginal cancer cell Line inhibitory activities. Expand
Isolation and structure of palstatin from the amazon tree Hymeneae palustris
Bioassay (P388 lymphocytic leukemia cell line and human cancer cell lines) guided separation of an extract prepared from the leaves of Hymenaea palustris Ducke led to the isolation of six cancer cellExpand
Flavones and flavone glycosides from Halophila johnsonii.
Qualitative comparison of the flavonoid distribution in the leaf and rhizome-root portions of the plant was investigated, with the aim of establishing the UV-protecting roles that flavonoids played in the sea grass. Expand
Search for new compounds and biologically active substances from Chinese marine organisms
In search of new pharmaceutically valuable substances from marine organisms, we have been engaged in chemical studies on the constituents of corals, sponges and algae collected in the South ChinaExpand
Isolation and structure of ruprechstyril from Ruprechtia tangarana.
The separation of an extract prepared from the stem bark and twigs of the previously uninvestigated Ruprechtia tangarana led to the isolation of a new isocarbostyril designated ruprechstyril, which exhibited cancer cell and microbial growth inhibition. Expand
Structure and biosynthesis of amphidinol 17, a hemolytic compound from Amphidinium carterae.
The polyol arm for AM17 displays a higher degree of nascent chain processing that shows similarities to amphidinolide biosynthesis, and was directly determined by feeding a single labeled substrate, [2-(13)C]acetate. Expand
Antineoplastic agents. 556. Isolation and structure of Coprinastatin 1 from Coprinus cinereus.
Cancer cell line bioassay-guided separation of an ethyl acetate extract prepared from a plant-associated fungus, Coprinus cinereus, led to the isolation of three new sesquiterpenes, coprinastatin 1Expand
Antineoplastic agents. 553. The Texas grasshopper Brachystola magna.
Examination of an extract prepared from the previously chemically uninvestigated Texas grasshopper Brachystola magna led to isolation of the cancer cell growth inhibitory pancratistatin, narciclasine, and ungeremine, which led to the X-ray crystal structure of this anticancer drug. Expand
Antineoplastic agents 582. Part 1: Isolation and structure of a cyclobutane-type sesquiterpene cancer cell growth inhibitor from Coprinus cinereus (Coprinaceae).
Bioassay-guided (murine P388 lymphocytic leukemia and human cancer cell lines) separation of an ethyl acetate extract prepared from the inky cap fungus Coprinus cinereus led to the isolation of threeExpand