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Insight into the mechanism of reproductive dysfunction caused by neonicotinoid pesticides.
TLDR
It is possible neonicotinoids affect the bird's reproductive system through oxidative stress, reflecting an imbalance between the production of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or easily repair the resulting damage.
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NOAEL-dose of a neonicotinoid pesticide, clothianidin, acutely induce anxiety-related behavior with human-audible vocalizations in male mice in a novel environment.
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Verification of the causal relationship between subchronic exposures to dinotefuran and depression-related phenotype in juvenile mice
TLDR
The subchronic exposure to DIN alone in juvenile male mice may not cause depression-like indication, and the most widely used NN in Japan, dinotefuran, induces depression.
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Spatiotemporal expression patterns of doublesex and mab-3 related transcription factor 1 in the chicken developing gonads and Mullerian ducts.
TLDR
The detailed spatiotemporal expression patterns of DMRT1 in the developing chicken urogenital systems throughout embryonic development are observed, suggesting its various roles in the development of urogensital tissues in the chicken embryo.
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Peripubertal exposure to the neonicotinoid pesticide dinotefuran affects dopaminergic neurons and causes hyperactivity in male mice
TLDR
Exposure to DIN in peripubertal male mice causes hyperactivity and a disturbance of dopaminergic signaling, suggesting a risk of developmental disorders via a disturbance in the monoamine systems.
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Morphological and phenotypical diversity of eosinophils in the rat ileum
Eosinophils are abundantly present in intestinal mucosa. However, the morphological characteristics of their cellular population are still largely unknown. In this study, we examine their…
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The combined effect of clothianidin and environmental stress on the behavioral and reproductive function in male mice
TLDR
The present study demonstrates that the behavioral and reproductive effects of CTD become more serious in combination with environmental stress, which may reflect the actual situation of multiple exposure.
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Unpredictable Chronic Stress-Induced Reproductive Suppression Associated with the Decrease of Kisspeptin Immunoreactivity in Male Mice
TLDR
The findings enhance the understanding of stress-induced reproductive suppression possibly mediated by kisspeptin in the ARC, a recently discovered upstream regulator of the reproductive endocrine feedback system.
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Quantitative elucidation of maternal-to-fetal transfer of neonicotinoid pesticide clothianidin and its metabolites in mice.
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Fetal exposure to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin transactivates aryl hydrocarbon receptor‐responsive element III in the tyrosine hydroxylase immunoreactive neurons of the mouse midbrain
TLDR
Fetal exposure to TCDD caused stable upregulation of TH via the AhR‐AHRE‐III signaling pathway and overgrowth of TH‐ir neurons in the midbrain, implying possible involvement in the etiology of neurodevelopmental disorders such as attention‐deficit/hyperactivity disorder (ADHD).
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