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- Publications
- Influence
Incidence and risk factors of atrial fibrillation in a surgical intensive care unit*
- P. Seguin, T. Signouret, B. Laviolle, B. Branger, Y. Mallédant
- Medicine
- Critical care medicine
- 1 March 2004
ObjectiveTo evaluate the incidence and risks factors of atrial fibrillation (AF). DesignProspective, observational study. SettingA surgical intensive care unit of a university hospital. PatientsAll… Expand
Factors associated with multidrug-resistant bacteria in secondary peritonitis: impact on antibiotic therapy.
- P. Seguin, B. Laviolle, +4 authors Y. Mallédant
- Medicine
- Clinical microbiology and infection : the…
- 1 October 2006
Secondary peritonitis includes community-acquired and nosocomial peritonitis. These intra-abdominal infections have a common pathogenesis but some microbiological differences, particularly with… Expand
Atrial fibrillation in trauma patients requiring intensive care
- P. Seguin, B. Laviolle, A. Maurice, C. Leclercq, Y. Mallédant
- Medicine
- Intensive Care Medicine
- 27 January 2006
AbstractObjectivesTo evaluate the incidence and risk factors of atrial fibrillation (AF) in trauma patients.Design and settingProspective observational study in a surgical intensive care unit… Expand
Prevalence and impact of frailty on mortality in elderly ICU patients: a prospective, multicenter, observational study
- P. L. Maguet, A. Roquilly, +10 authors P. Séguin
- Medicine
- Intensive Care Medicine
- 21 March 2014
PurposeFrailty is a recent concept used for evaluating elderly individuals. Our study determined the prevalence of frailty in intensive care unit (ICU) patients and its impact on the rate of… Expand
Clinical review: The liver in sepsis
- N. Nesseler, Y. Launey, C. Aninat, F. Morel, Y. Mallédant, P. Seguin
- Medicine
- Critical Care
- 30 October 2012
During sepsis, the liver plays a key role. It is implicated in the host response, participating in the clearance of the infectious agents/products. Sepsis also induces liver damage through… Expand
Effect of oropharyngeal decontamination by povidone-iodine on ventilator-associated pneumonia in patients with head trauma*
- P. Seguin, M. Tanguy, B. Laviolle, O. Tirel, Y. Mallédant
- Medicine
- Critical care medicine
- 1 May 2006
Objective:To evaluate the effect of a regular oropharyngeal application of povidone-iodine on the prevalence of ventilator-associated pneumonia in patients with severe head trauma. Design:Prospective… Expand
The Effects of Small-Dose Ketamine on Morphine Consumption in Surgical Intensive Care Unit Patients After Major Abdominal Surgery
- N. Guillou, M. Tanguy, P. Seguin, B. Branger, J. Campion, Y. Mallédant
- Medicine
- Anesthesia and analgesia
- 1 September 2003
In a randomized, double-blinded study, we evaluated the analgesic effect of ketamine in the management of pain in a surgical intensive care unit after major abdominal surgery. Patients received… Expand
Hydrocortisone therapy for patients with multiple trauma: the randomized controlled HYPOLYTE study.
- A. Roquilly, P. Mahe, +13 authors K. Asehnoune
- Medicine
- JAMA
- 23 March 2011
CONTEXT
The role of stress-dose hydrocortisone in the management of trauma patients is currently unknown.
OBJECTIVE
To test the efficacy of hydrocortisone therapy in trauma patients.
DESIGN,… Expand
Determination of capillary hemoglobin levels using the HemoCue system in intensive care patients.
- P. Seguin, A. Kleiber, C. Chanavaz, J. Morcet, Y. Mallédant
- Medicine
- Journal of critical care
- 1 August 2011
PURPOSE
The study aimed to compare hemoglobin (Hb) values determined using the portable HemoCue system (HemoCue Hb 201+; HemoCue AB, Ängelholm, Sweden) with laboratory Hb level determination.
… Expand
Modulation of airway remodeling-associated mediators by the antifibrotic compound, pirfenidone, and the matrix metalloproteinase inhibitor, batimastat, during acute lung injury in mice.
- M. Corbel, J. Lanchou, N. Germain, Y. Mallédant, E. Boichot, V. Lagente
- Medicine
- European journal of pharmacology
- 24 August 2001
Matrix metalloproteinases (MMPs) are potent to degrade basement membrane collagen associated with acute lung injury in inflammatory processes. We have investigated effects of pirfenidone,… Expand