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Crystal structure of FtsA from Staphylococcus aureus
The bacterial cell‐division protein FtsA anchors FtsZ to the cytoplasmic membrane. But how FtsA and FtsZ interact during membrane division remains obscure. We have solved 2.2 Å resolution crystalExpand
Identification of the key interactions in structural transition pathway of FtsZ from Staphylococcus aureus.
The tubulin-homolog protein FtsZ is essential for bacterial cell division. FtsZ polymerizes to form protofilaments that assemble into a contractile ring-shaped structure in the presence of GTP.Expand
How and how much can Hoechst 33258 cause unwinding in a DNA duplex?
The effect of Hoechst 33258 binding on the geometry of a DNA duplex (plasmid pBR322) has been examined using topoisomerase II relaxation followed by gel electrophoresis. Of this drug-DNA system,Expand
Structural Flexibility of an Inhibitor Overcomes Drug Resistance Mutations in Staphylococcus aureus FtsZ.
In the effort to combat antibiotic resistance, inhibitors of the essential bacterial protein FtsZ have emerged as a promising new class of compounds with clinical potential. One such FtsZ inhibitorExpand
Synthesis, spectroscopic, electrochemical and anti-HIV studies of some mononuclear and dinuclear FeIII complexes of 3-hydroxy-4'-benzyloxy flavonecontaining oxygen, nitrogen and sulphur donors as
Complex of Fe111 with 3-hydroxy-4'-benzyloxy-flavone (LH) (1) was allowed to react with DMSO (2), 2-mercaptobenzimidazole (MBZH) (3), sodiumdithiacarbamate (NaDTC) (4) and pentane-2,4-dione (acacH)Expand
The average unwinding angle of DNA duplex produced by the binding of chromomycin A3.
The effect of chromomycin A3 binding on the geometry of DNA duplex (plasmid pBR322) has been examined using topoisomerase I relaxation followed by gel electrophoresis. To determine the equilibriumExpand
Synthesis, Crystal Structure, and Some Spectrochemical Properties of Optically Active S-Bridged Trinuclear Complex ΔΔ-[Ni{Co(aet)2(R-pn)}2]4+ (aet = 2-Aminoethanethiolate, R–pn =
The reaction of cis-[CoCl2(R-pn)2]+ (R–pn = (R)–1,2-propanediamine) with [Ni(aet)2] (aet = 2–aminoethanethiolate) in water stereoselectively gave an S-bridged trinuclear complex,Expand