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S Phase Activation of the Histone H2B Promoter by OCA-S, a Coactivator Complex that Contains GAPDH as a Key Component
We have isolated and functionally characterized a multicomponent Oct-1 coactivator, OCA-S which is essential for S phase-dependent histone H2B transcription. The p38 component of OCA-S binds directlyExpand
Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1
MAMMALIAN cell-cycle control by antimitogenic signals involves p21Cip1/WAF1(refs 1–4), p27Kip1 (refs 5,6) andp57Kip2(refs 7,8) a family of proteins that bind to and inhibit cyclin-dependent kinasesExpand
ABT-450/r-ombitasvir and dasabuvir with or without ribavirin for HCV.
BACKGROUND The interferon-free regimen of ABT-450 with ritonavir (ABT-450/r), ombitasvir, and dasabuvir with or without ribavirin has shown efficacy in inducing a sustained virologic response in aExpand
A unified enhanced particle swarm optimization-based virtual network embedding algorithm
We propose a unified enhanced particle swarm optimization-based VN embedding algorithm, called VNE-UEPSO, to solve these two models irrespective of the support for path splitting. Expand
Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo
The Akt kinases are central nodes in signal transduction pathways that are important for cellular transformation and tumor progression. We report the development of a series of potent and selectiveExpand
Intravitreal injection of erythropoietin protects both retinal vascular and neuronal cells in early diabetes.
PURPOSE To explore and evaluate the protective effect of erythropoietin (EPO) on retinal cells of chemically induced diabetic rats after EPO was injected intravitreally at the onset of diabetes. Expand
Integration of tight junctions and claudins with the barrier functions of the retinal pigment epithelium
The retinal pigment epithelium (RPE) forms the outer blood-retinal barrier by regulating the movement of solutes between the fenestrated capillaries of the choroid and the photoreceptor layer of theExpand
Effects of culture conditions on heterogeneity and the apical junctional complex of the ARPE-19 cell line.
PURPOSE ARPE-19 is a spontaneously transformed cell line of human RPE that is widely studied. This report examines its suitability for studying the tight junctions of the RPE. METHODS ARPE-19 wasExpand
AIP1/DAB2IP, a Novel Member of the Ras-GAP Family, Transduces TRAF2-induced ASK1-JNK Activation*
Previously we have shown that ASK-interacting protein 1 (AIP1, also known as DAB2IP), a novel member of the Ras-GAP protein family, mediates TNF-induced activation of ASK1-JNK signaling pathway.Expand
On the Evolutionary History, Population Genetics and Diversity among Isolates of Salmonella Enteritidis PFGE Pattern JEGX01.0004
Facile laboratory tools are needed to augment identification in contamination events to trace the contamination back to the source (traceback) of Salmonella enterica subsp. enterica serovarExpand