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Circulating lncRNA UCA1 Promotes Malignancy of Colorectal Cancer via the miR-143/MYO6 Axis
  • Y. Luan, X. Li, +6 authors Lu Jia
  • Biology, Medicine
  • Molecular therapy. Nucleic acids
  • 24 December 2019
Exosomes mediate cell-cell crosstalk in cancer progression by transferring a variety of biomolecules, including long noncoding RNAs (lncRNAs). Long non-coding RNA urothelial carcinoma-associatedExpand
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Effects of Codonopis bulleynana forest ex diels on Deferribacteres in constipation predominant intestine tumor: Differential analysis
  • Y. Li, Y. Luan, +4 authors Z. Xiong
  • Biology, Medicine
  • Saudi journal of biological sciences
  • 6 December 2018
As a complicated micro-ecosystem, gut microbes are closely related to metabolic disease, immune disease and tumor (such as constipation. Long-term constipation would cause intestinal mucosal injury,Expand
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Codonopis bulleynana Forest ex Diels inhibits autophagy and induces apoptosis of colon cancer cells by activating the NF-κB signaling pathway
  • Y. Luan, Y. Li, +4 authors Y. Cao
  • Chemistry, Medicine
  • International journal of molecular medicine
  • 21 December 2017
Despite its favorable clinical efficacy, oxaliplatin-based chemotherapy frequently results in treatment withdrawal and induces liver damage in colon cancer. Therefore, it is important to developExpand
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Tsoong induces apoptosis and inhibits proliferation, migration and invasion of pancreatic ductal adenocarcinoma cells
The roots of Codonopsis cordifolioidea (classified as campanulaceae cordifolioidea), locally known as Tsoong, have been used as a tonic food. The major components isolated from Tsoong have beenExpand
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The effect of Codonopis bulleynana Forest ex Diels on chronically constipated mice
To verify the laxative effect of Codonopsis bulleyana and its effect on intestinal microbiota, a long-term constipation model was established using 3.0 mg/kg loperamide hydrochloride, after which,Expand
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RNA sequencing reveals the differences between chemical and chronic constipation induction of intestinal tumor
Constipation is a common clinical symptom and it is a highly frequent complication in patients with chronic gastrointestinal disorder and intestinal tumor. The chemicals such as DMHExpand
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Isorhamnetin in Tsoong blocks Hsp70 expression to promote apoptosis of colon cancer cells
The roots of Codonopis bulleynana Forest ex diels (cbFed), locally known as Tsoong, have been used as a tonic food. Tsoong has wide range of pharmacological effects, including anticancer efficacy. InExpand
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Structural changes of gut microbiota in mice with chronic constipation and intestinal tumor
Background: Constipation is a highly frequent complication in patients with chronic gastrointestinal disorder and intestinal cancer. The purpose of this study was to evaluate the changes of gutExpand
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The research on the mechanism of Tsoong inhibiting for colon cancer
The roots of Codonopis bulleynana Forest ex diels (cbFed), locally known as Tsoong, have been used as a tonic food. Tsoong has wide range of pharmacological effects, including anticancer effects. InExpand
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Changes of intestinal microflora diversity in diarrhea model of KM mice and effects of Psidium guajava L. as the treatment agent for diarrhea.
OBJECTIVES This study aimed to explore the effects of Psidium guajava L. extracts on mice diarrhea model and changes in their intestinal microflora diversity. METHODS Mice diarrhea model wasExpand
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