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Development and clinical application of a rapid IgM‐IgG combined antibody test for SARS‐CoV‐2 infection diagnosis
A rapid and simple point‐of‐care lateral flow immunoassay that can detect immunoglobulin M (IgM) and IgG antibodies simultaneously against SARS‐CoV‐2 virus in human blood within 15 minutes which can detect patients at different infection stages is developed. Expand
The MRC IEU OpenGWAS data infrastructure
The OpenGWAS database is presented, an open source, open access, scalable and high-performance cloud-based data infrastructure that imports and publishes complete GWAS summary datasets and metadata for the scientific community. Expand
Effect of welding sequence on residual stress and distortion in flat-bar stiffened plates
Numerical simulation based on finite element modelling is used to study the influence of welding sequences on the distribution of residual stress and distortion generated when welding a flat-barExpand
Agreement between endoscopic and histological gastric atrophy scores
The strength of agreement between the endoscopic atrophic border (EAB) and histological atrophy scores is not worse than the interobserver histological agreement between two pathologists. Expand
Oral Microbiota Perturbations Are Linked to High Risk for Rheumatoid Arthritis
A characteristic compositional change of salivary microbes in individuals at high-risk for RA is observed, suggesting that oral microbiota dysbiosis occurs in the “pre-clinical” stage of RA and are correlated with systemic autoimmune features. Expand
Protective Effects of Lanosterol Synthase Up-Regulation in UV-B-Induced Oxidative Stress
UV-B exposure induced oxidative injury and resulted in crystallin denaturation and apoptosis in lens epithelial cells, and LSS might play a protective role during the early stages of this process and could be an important target in the cataract prevention. Expand
Morphological, histological and molecular characterization of three Myxobolus species (Cnidaria: Myxosporea) from silver carp Hypophthalmichthys molitrix Valenciennes and bighead carp
Three Myxobolus species were obtained from silver carp Hypophthalmichthys molitrix Valenciennes and bighead carp and robustly clustered together in Cyprinid group and Asia group and morphological, histological and molecular methods were supplemented. Expand
Bioinformatic Analysis of Neuroimmune Mechanism of Neuropathic Pain
The present study helps to better understand the neuroimmune mechanism of neuropathic pain and provides some novel insights on NP treatment, such as modulation of microglia polarization and targeting bone resorption. Expand
Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues
Children have elevated frequencies of pathogen-specific class-switched memory B cells, including SARS-CoV-2-binding clones, which extend age-related and anatomical mapping of human humoral pathogenic-specific immunity. Expand
X-ray-Based Techniques to Study the Nano-Bio Interface.
This work describes different X-ray-based methodologies and their potentials for application to investigate the nano-bio interface and discusses current limitations and how they might be overcome, particularly for future use in vivo. Expand